Gene Symbol |
NES
|
Entrez Gene |
10763
|
Alt Symbol |
Nbla00170
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
nestin
|
Other Description |
-
|
Swissprots |
Q3LIF5 P48681 Q5SYZ6 O00552
|
Accessions |
AAB64426 CAA46780 EAW52923 EAW52924 EAW52925 EAW52926 P48681 AB073350 BAE45713 AF086454 AK025494 BAB15153 AL120767 BC032580 AAH32580 BC051373 BC108285 AAI08286 BC142611 AAI42612 BF340882 BG912782 BQ678387 BU554136 GU014842 ACX32329 NM_006617 NP_006608
|
Function |
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). {ECO:0000250}.
|
Tissue Specificity |
CNS stem cells.
|