Gene Symbol | NES |
---|---|
Entrez Gene | 10763 |
Alt Symbol | Nbla00170 |
Species | Human |
Gene Type | protein-coding |
Description | nestin |
Other Description | - |
Swissprots | Q3LIF5 P48681 Q5SYZ6 O00552 |
Accessions | AAB64426 CAA46780 EAW52923 EAW52924 EAW52925 EAW52926 P48681 AB073350 BAE45713 AF086454 AK025494 BAB15153 AL120767 BC032580 AAH32580 BC051373 BC108285 AAI08286 BC142611 AAI42612 BF340882 BG912782 BQ678387 BU554136 GU014842 ACX32329 NM_006617 NP_006608 |
Function | Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). {ECO:0000250}. |
Tissue Specificity | CNS stem cells. |
nestin CRISPR/Cas9 KO Plasmid (h) - sc-400156 from Santa Cruz Biotechnology
|
||||||||
nestin HDR Plasmid (h) - sc-400156-HDR from Santa Cruz Biotechnology
|
||||||||
nestin Double Nickase Plasmid (h) - sc-400156-NIC from Santa Cruz Biotechnology
|
||||||||
nestin Double Nickase Plasmid (h2) - sc-400156-NIC-2 from Santa Cruz Biotechnology
|
||||||||
nestin CRISPR Activation Plasmid (h) - sc-400156-ACT from Santa Cruz Biotechnology
|
||||||||
nestin CRISPR Activation Plasmid (h2) - sc-400156-ACT-2 from Santa Cruz Biotechnology
|
||||||||
nestin Lentiviral Activation Particles (h) - sc-400156-LAC from Santa Cruz Biotechnology
|
||||||||
nestin Lentiviral Activation Particles (h2) - sc-400156-LAC-2 from Santa Cruz Biotechnology
|
||||||||
nestin siRNA (h) - sc-36032 from Santa Cruz Biotechnology
|
||||||||
nestin shRNA Plasmid (h) - sc-36032-SH from Santa Cruz Biotechnology
|
||||||||
nestin shRNA (h) Lentiviral Particles - sc-36032-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU157031 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN15211 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15211 from Sigma-Aldrich
|
||||||||
NES siRNA (Human) - CRH7333 from Cohesion Biosciences
|
||||||||
nestin CRISPR/Cas9 KO Plasmid (h2) - sc-400156-KO-2 from Santa Cruz Biotechnology
|
||||||||
nestin HDR Plasmid (h2) - sc-400156-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human Nes (NM_006617.1) - SHH351396 from Creative biogene
|
||||||||
NES shRNA Plasmid (Human) - CHH7333 from Cohesion Biosciences
|
||||||||
NES miRNA 3'UTR clone - MiUTR1H-06722 from Creative biogene
|