ANO6

Gene Symbol	ANO6
Entrez Gene	196527
Alt Symbol	BDPLT7, SCTS, TMEM16F
Species	Human
Gene Type	protein-coding
Description	anoctamin 6
Other Description	SCAN channel|anoctamin-6|small-conductance calcium-activated nonselective cation channel|transmembrane protein 16F
Swissprots	Q4KMQ2 E9PB30 E7ENK4 A6NNM6 E9PCT2 Q8N3Q2 B9EGG0
Accessions	Q4KMQ2 AA332109 AK095979 AK126409 BAG54324 AK302819 BAG64017 AK303996 BAG64913 AK310641 AL832340 AL833405 CAD38638 BC042383 BC063576 BC073891 BC098410 AAH98410 BC136445 AAI36446 XM_005268706 XP_005268763 XM_005268707 XP_005268764 XM_011538024 XP_011536326 NM_001025356 NP_001020527 NM_001142678 NP_001136150 NM_001142679 NP_001136151 NM_001204803 NP_001191732 NM_001142680
Function	Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes. {ECO:0000250|UniProtKB:Q6P9J9, ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21107324, ECO:0000269|PubMed:21908539, ECO:0000269|PubMed:22006324, ECO:0000269|PubMed:22946059}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21107324, ECO:0000269|PubMed:22075693, ECO:0000269|PubMed:22946059}; Multi-pass membrane protein {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21107324, ECO:0000269|PubMed:22075693, ECO:0000269|PubMed:22946059}. Note=Shows an intracellular localization according to PubMed:22075693.
Tissue Specificity	Expressed in embryonic stem cell, fetal liver, retina, chronic myologenous leukemia and intestinal cancer. {ECO:0000269|PubMed:15067359}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics

Human ANO6 ELISA Kit (Sandwich ELISA) - LS-F7683 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.127 ng/ml Range 0.313-20 ng/ml

Human Anoctamin 6 ELISA Kit - abx150674 from Abbexa Category ELISA Kit Sensitivity 0.127 ng/ml Range 0.313 ng/ml - 20 ng/ml

Anoctamin 6 (ANO6), Human, ELISA Kit - SEF813Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.127ng/mL Range 0.312-20ng/mL

Anoctamin-6 (ANO6), Human, ELISA Kit - E01A1532 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 0.5-10ng/ml

Anoctamin 6, ELISA Kit - MBS100660 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 6, ELISA Kit - MBS056384 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 6, ELISA Kit - MBS072017 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 6, ELISA Kit - MBS105072 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 6, ELISA Kit - MBS095925 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 6, ELISA Kit - MBS085691 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 6, ELISA Kit - MBS053740 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 6 (ANO6), ELISA Kit - MBS7225865 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Anoctamin 6 (ANO6), ELISA Kit - MBS2023354 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.127ng/mL. Range 0.313-20ng/mL

ELISA Kit for Anoctamin 6 (ANO6) - SEF813Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.127ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Anoctamin 6 (ANO6) - SEF813Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.127ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human Anoctamin 6 (ANO6) ELISA Kit - EKU02438 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.127 ng/mL Range 0.312-20 ng/mL

Anoctamin 6 (ANO6), Human, ELISA Kit - DL-ANO6-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human ANO6 ELISA Kit - abx572616 from Abbexa Category ELISA Kit Sensitivity 0.127 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human ANO6 ELISA Kit - E002463 from Biobool Category ELISA Kit Sensitivity Typically less than 0.127ng/mL.

ANO6 ELISA Kit (Human) (OKCD00984) - OKCD00984 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.127 ng/mL Range 0.312-20 ng/mL

Anoctamin 6 (ANO6), ELISA Kit - MBS453455 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.127ng/mL Range 0.312-20ng/mL

Anoctamin 6 (ANO6), ELISA Kit - MBS9375942 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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