VTI1A

Gene Symbol VTI1A
Entrez Gene 143187
Alt Symbol MMDS3, MVti1, VTI1RP2, Vti1-rp2
Species Human
Gene Type protein-coding
Description vesicle transport through interaction with t-SNAREs 1A
Other Description SNARE Vti1a-beta protein|vesicle transport through interaction with t-SNAREs homolog 1A|vesicle transport v-SNARE protein Vti1-like 2
Swissprots Q96AJ9 B4E137 Q5W0D7 A2A307
Accessions EAW49524 EAW49525 Q96AJ9 AI610960 AI797732 AK095476 AK303646 BAG64649 BC017052 AAH17052 BC064614 BC067241 BI909044 DA324398 DA472521 HG503273 JF432603 ADZ15820 XM_005269543 XP_005269600 XM_005269544 XP_005269601 XM_005269545 XP_005269602 XM_005269546 XP_005269603 XM_005269547 XP_005269604 XM_005269548 XP_005269605 XM_006717636 XP_006717699 XM_006717637 XP_006717700 XM_011539328 XP_011537630 XM_011539329 XP_011537631 XM_011539330 XP_011537632 XM_011539331 XP_011537633 XM_011539332 XP_011537634 XM_011539333 XP_011537635 NM_145206 NP_660207
Function V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence. {ECO:0000269|PubMed:18195106, ECO:0000269|PubMed:19138172}.
Subcellular Location Cytoplasmic vesicle {ECO:0000269|PubMed:19138172}. Golgi apparatus membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}.
Top Pathways SNARE interactions in vesicular transport

Vti1a (D8U3M) Rabbit mAb - 14764 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D8U3M
Western blot analysis of extracts from various cell lines and tissues using Vti1a (D8U3M) Rabbit mAb.

Vti1a Antibody - 13098 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing Myc-tagged full-length human Vti1a (hVti1a-Myc; +) , using Vti1a Antibody.

v-SNARE Vti1a (G-13) - sc-160902 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

v-SNARE Vti1a (N-12) - sc-160903 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

v-SNARE Vti1a (45) - sc-136117 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
v-SNARE Vti1a (45): sc-136117. Western blot analysis of v-SNARE Vti1a expression in rat brain tissue extract.

Anti-VTI1A antibody - ab177117 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VTI1A antibody (ab177117) at 1/500 dilution + HeLa lysate

Anti-VTI1A antibody - ab84556 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-VTI1A antibody (ab84556) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal muscle lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-VTI1A antibody - ab195596 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
Anti-VTI1A antibody (ab195596) at 1/500 dilution + HeLa cell lysate

Anti-VTI1A antibody - ab138307 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VTI1A antibody (ab138307) at 1/500 dilution + HUVEC cell lysate at 30 µg

Anti-VTI1A antibody [1E3] - ab156773 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E3
All lanes : Anti-VTI1A antibody [1E3] (ab156773) at 1/4000 dilutionLane 1 : Lysate from HEK293T cells transfected with an empty vectorLane 2 : Lysate from HEK293T cells transfected with a vector bearing VTI1ALysates/proteins at 5 µg per lane.

Anti-VTI1A antibody [1F4] - ab156793 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F4
All lanes : Anti-VTI1A antibody [1F4] (ab156793) at 1/200 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY VTI1A cDNALysates/proteins at 5 µg per lane.

Anti-VTI1A Antibody (C-Terminus, APC) - LS-C246367 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VTI1A Antibody (C-Terminus, AP) - LS-C246366 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VTI1A Antibody (C-Terminus, FITC) - LS-C246369 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VTI1A Antibody (C-Terminus, Biotin) - LS-C246368 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VTI1A Antibody (C-Terminus, PE) - LS-C246370 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VTI1A Antibody (C-Terminus, Azide-free, HRP) - LS-C247967 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VTI1A Antibody (C-Terminus) - LS-C329086 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VTI1A Antibody (aa31-80) - LS-C291421 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-VTI1A Antibody (aa21-70) - LS-C200817 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HUVEC cells using VTI1A antibody.

Anti-VTI1A Antibody (N-Terminus) - LS-C102475 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
VTI1A antibody LS-C102475 Western blot of Fetal Muscle lysate.

Anti-VTI1A Antibody (clone 1E3) - LS-C337968 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY VTI1A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-VTI1A.

Anti-VTI1A Antibody (aa140-169) - LS-C160556 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human lung carcinoma with VTI1A Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-VTI1A Antibody (clone 1F4) - LS-C337982 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F4
IHC of paraffin-embedded Carcinoma of Human pancreas tissue using anti-VTI1A mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

VTI1A Antibody - NBP1-91431 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: VTI1A Antibody [NBP1-91431] - Human Muscle lysate, concentration 0.2-1 ug/ml.
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