Gene Symbol | MLLT1 |
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Entrez Gene | 4298 |
Alt Symbol | ENL, LTG19, YEATS1 |
Species | Human |
Gene Type | protein-coding |
Description | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 |
Other Description | CTC-503J8.6|ENL/MLL fusion|MLLT1/MLL fusion|YEATS domain-containing protein 1|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1|protein ENL |
Swissprots | Q14768 Q03111 |
Accessions | EAW69106 Q03111 AF373587 AL365410 CAB96954 BC047008 BC063667 BC084564 BC146318 AAI46319 BC146385 AAI46386 BC148806 AAI48807 D14539 BAA03406 DQ224342 ABB29494 L04285 AAA58457 XM_011528021 XP_011526323 XM_011528022 XP_011526324 XM_011528023 XP_011526325 NM_005934 NP_005925 |
Function | Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948}. |
Subcellular Location | Nucleus. |
Top Pathways | Transcriptional misregulation in cancer |
MLLT1/ENL (D9M4B) Rabbit mAb - 14893 from Cell Signaling Technology
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MLLT1/ENL Antibody - 12141 from Cell Signaling Technology
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ENL (D-6) - sc-393196 from Santa Cruz Biotechnology
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ENL (F-20) - sc-32366 from Santa Cruz Biotechnology
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ENL (H-58) - sc-366888 from Santa Cruz Biotechnology
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Anti-MLLT1 antibody - ab49052 from Abcam
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Anti-MLLT1 antibody - ab71477 from Abcam
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Anti-MLLT1 antibody - ab111864 from Abcam
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Anti-MLLT1 antibody - ab55446 from Abcam
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Anti-ENL / MLLT1 Antibody (aa523-552) - LS-C100428 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa325-375) - LS-C289021 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa325-375) - LS-C286855 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (clone 3H2) - LS-C197687 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa538-553) IHC-plus⢠- LS-B868 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa530-559, AP) - LS-C223287 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa530-559, APC) - LS-C223289 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa530-559, FITC) - LS-C223291 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa357-406) - LS-C31755 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa530-559, PE) - LS-C223295 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa530-559, Biotin) - LS-C223290 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa530-559, Azide-free, HRP) - LS-C223292 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa530-559) - LS-C329838 from LifeSpan Bioscience
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Anti-ENL / MLLT1 Antibody (aa150-200) - LS-C289022 from LifeSpan Bioscience
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MLLT1 Antibody (3H2) - H00004298-M01 from Novus Biologicals
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MLLT1 Antibody - NBP1-84840 from Novus Biologicals
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