MLLT1

Gene Symbol MLLT1
Entrez Gene 4298
Alt Symbol ENL, LTG19, YEATS1
Species Human
Gene Type protein-coding
Description myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
Other Description CTC-503J8.6|ENL/MLL fusion|MLLT1/MLL fusion|YEATS domain-containing protein 1|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1|protein ENL
Swissprots Q14768 Q03111
Accessions EAW69106 Q03111 AF373587 AL365410 CAB96954 BC047008 BC063667 BC084564 BC146318 AAI46319 BC146385 AAI46386 BC148806 AAI48807 D14539 BAA03406 DQ224342 ABB29494 L04285 AAA58457 XM_011528021 XP_011526323 XM_011528022 XP_011526324 XM_011528023 XP_011526325 NM_005934 NP_005925
Function Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948}.
Subcellular Location Nucleus.
Top Pathways Transcriptional misregulation in cancer

ENL CRISPR/Cas9 KO Plasmid (h) - sc-408751 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENL HDR Plasmid (h) - sc-408751-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENL Double Nickase Plasmid (h) - sc-408751-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENL Double Nickase Plasmid (h2) - sc-408751-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENL CRISPR Activation Plasmid (h) - sc-408751-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENL CRISPR Activation Plasmid (h2) - sc-408751-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENL Lentiviral Activation Particles (h) - sc-408751-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENL Lentiviral Activation Particles (h2) - sc-408751-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ENL siRNA (h) - sc-44791 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ENL shRNA Plasmid (h) - sc-44791-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ENL shRNA (h) Lentiviral Particles - sc-44791-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MLLT1 RNAi - H00004298-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN14401 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14401 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MLLT1 siRNA (Human) - CRH2916 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MLLT1 (NM_005934.3) - SHH342564 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MLLT1(NM_005934.3) - SHH192089 from Creative biogene

Category siRNA
Species Reactivities Human

Human MLLT1 siRNA - orb263418 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MLLT1 shRNA Plasmid (Human) - CHH2916 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MLLT1 miRNA 3'UTR clone - MiUTR1H-06327 from Creative biogene

Species Reactivities Human
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