| Gene Symbol |
MLLT1
|
| Entrez Gene |
4298
|
| Alt Symbol |
ENL, LTG19, YEATS1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
|
| Other Description |
CTC-503J8.6|ENL/MLL fusion|MLLT1/MLL fusion|YEATS domain-containing protein 1|myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1|protein ENL
|
| Swissprots |
Q14768 Q03111
|
| Accessions |
EAW69106 Q03111 AF373587 AL365410 CAB96954 BC047008 BC063667 BC084564 BC146318 AAI46319 BC146385 AAI46386 BC148806 AAI48807 D14539 BAA03406 DQ224342 ABB29494 L04285 AAA58457 XM_011528021 XP_011526323 XM_011528022 XP_011526324 XM_011528023 XP_011526325 NM_005934 NP_005925
|
| Function |
Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948}.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
Transcriptional misregulation in cancer
|