TRIP4

Gene Symbol TRIP4
Entrez Gene 9325
Alt Symbol ASC-1, ASC1, HsT17391, ZC2HC5
Species Human
Gene Type protein-coding
Description thyroid hormone receptor interactor 4
Other Description TR-interacting protein 4|TRIP-4|activating signal cointegrator 1|thyroid receptor interacting protein 4|thyroid receptor-interacting protein 4|zinc finger, C2HC5-type
Swissprots Q9UKH0 B2RAS0 Q15650 Q96ED7
Accessions EAW77684 EAW77685 Q15650 AK000433 AK314319 BAG36967 BC012448 AAH12448 BG166305 BQ225927 CA425850 EU446746 ABZ92275 L40371 AAC41738 XM_005254789 XP_005254846 XR_243130 NM_016213 NP_057297
Function Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation (By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B (PubMed:12077347). {ECO:0000250|UniProtKB:Q9QXN3, ECO:0000269|PubMed:10454579, ECO:0000269|PubMed:12077347, ECO:0000269|PubMed:25219498}.
Subcellular Location Nucleus {ECO:0000269|PubMed:10454579, ECO:0000269|PubMed:20873783}. Cytoplasm, cytosol {ECO:0000269|PubMed:10454579, ECO:0000269|PubMed:20873783}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20873783}. Note=Cytoplasmic under conditions of serum deprivation (PubMed:10454579). Colocalizes with NEK6 in the centrosome (PubMed:20873783). {ECO:0000269|PubMed:10454579, ECO:0000269|PubMed:20873783}.

TRIP-4/ASC-1 Antibody - 2333 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

ASC-1 (F-8) - sc-365202 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ASC-1 (F-8): sc-365202. Western blot analysis of ASC-1 expression in K-562 whole cell lysate.

ASC-1 (D-4) - sc-365611 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ASC-1 (D-4): sc-365611. Western blot analysis of ASC-1 expression in non-transfected: sc-117752 (A) and mouse ASC-1 transfected: sc-118583 (B) 293T whole cell lysates.

ASC-1 (C-18) - sc-11235 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ASC-1 (H-300) - sc-292670 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ASC-1 (H-300): sc-292670. Western blot analysis of ASC-1 expression in non-transfected: sc-117752 (A) and mouse ASC-1 transfected: sc-118583 (B) 293T whole cell lysates.

ASC-1 (K-16) - sc-11234 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ASC-1 (K-16): sc-11234. Western blot analysis of ASC-1 expression in non-transfected: sc-117752 (A) and mouse ASC-1 transfected: sc-118583 (B) 293T whole cell lysates.

ASC-1 (N-20) - sc-11232 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ASC-1 (N-20): sc-11232. Immunoperoxidase staining of formalin fixed, paraffin-embedded human colon tissue showing nuclear and cytoplasmic staining of glandular cells and nuclear staining of endothelial cells.

Anti-ASC1 antibody - ab70627 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ASC1 antibody (ab70627) at 0.4 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgLane 5 : NIH3T3 whole cell lysate at 50 µg

Anti-ASC1 antibody - ab64966 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ASC1 antibody (ab64966) at 1/500 dilutionLane 1 : extracts from K562 cells, without immunising peptideLane 2 : extracts from K562 cells, with immunising peptide

Anti-ASC1 antibody - ab129643 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ASC1 antibody (ab129643) at 1/100 dilution + SK-BR-3 cell line lysate at 35 µg

Anti-ASC1 antibody - ab175442 from Abcam

Prices $242.00
Sizes 200 µl
Host Goat
Clonality Polyclonal

Anti-ASC1 antibody - C-terminal - ab199886 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-ASC1 antibody - C-terminal (ab199886) at 1/1000 dilutionLane 1 : Mouse brain total cell extractLane 2 : Mouse thymus total cell extractLane 3 : HeLa total cell extractLane 4 : Jurkat total cell extract

Anti-TRIP4 / ASC-1 Antibody (aa75-125) - LS-C69298 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa94-106) - LS-C186621 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa453-464) - LS-C186622 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa194-222, AP) - LS-C272281 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa194-222, FITC) - LS-C272284 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa194-222, APC) - LS-C272283 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa191-240) - LS-C31300 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: 293T Cell Lysate

Anti-TRIP4 / ASC-1 Antibody (aa194-222, Azide-free, HRP) - LS-C272286 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa194-222, Biotin) - LS-C272285 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa194-222, PE) - LS-C272287 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa225-275) - LS-C287691 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa75-125) - LS-C287124 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIP4 / ASC-1 Antibody (aa193-222) - LS-C325974 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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