TRIP4

Gene Symbol	TRIP4
Entrez Gene	9325
Alt Symbol	ASC-1, ASC1, HsT17391, ZC2HC5
Species	Human
Gene Type	protein-coding
Description	thyroid hormone receptor interactor 4
Other Description	TR-interacting protein 4|TRIP-4|activating signal cointegrator 1|thyroid receptor interacting protein 4|thyroid receptor-interacting protein 4|zinc finger, C2HC5-type
Swissprots	Q9UKH0 B2RAS0 Q15650 Q96ED7
Accessions	EAW77684 EAW77685 Q15650 AK000433 AK314319 BAG36967 BC012448 AAH12448 BG166305 BQ225927 CA425850 EU446746 ABZ92275 L40371 AAC41738 XM_005254789 XP_005254846 XR_243130 NM_016213 NP_057297
Function	Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498). Also involved in androgen receptor transactivation (By similarity). Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF- kappa-B (PubMed:12077347). {ECO:0000250|UniProtKB:Q9QXN3, ECO:0000269|PubMed:10454579, ECO:0000269|PubMed:12077347, ECO:0000269|PubMed:25219498}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:10454579, ECO:0000269|PubMed:20873783}. Cytoplasm, cytosol {ECO:0000269|PubMed:10454579, ECO:0000269|PubMed:20873783}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20873783}. Note=Cytoplasmic under conditions of serum deprivation (PubMed:10454579). Colocalizes with NEK6 in the centrosome (PubMed:20873783). {ECO:0000269|PubMed:10454579, ECO:0000269|PubMed:20873783}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ASC1 full length protein - ab152970 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

TRIP4 / ASC-1 Antibody Blocking Peptide - LS-E4326 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TRIP4 / ASC-1 Antibody Blocking Peptide - LS-E12791 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human ASC1 Protein - H00009325-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TRIP4-Antibody-Center-Blocking-Peptide - BP16622c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ASC1 Peptide - AC21-2954-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ASC1 Peptide - AC21-2955-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ASC1 / TRIP4 - H00009325-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ASC1 / TRIP4 - H00009325-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TRIP4 fusion protein - Ag2987 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human TRIP4, GST-tagged - TRIP4-3423H from Creative Biomart Category Protein Source E.coli Species Human

ASC-1 (G105) Peptide - BS2072P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Activating signal cointegrator 1(TRIP4) - CSB-YP618991HU CSB-EP618991HU CSB-BP618991HU CSB-MP618991HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Activating signal cointegrator 1 (TRIP4) - MBS1457196 from MyBioSource Category Protein Prices $1,255.00, $1,255.00, $1,710.00, $1,710.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Orangutan

Activating signal cointegrator 1 complex subunit 3(ascc3) ,partial - MBS1401320 from MyBioSource Category Protein Prices $2,300.00, $2,300.00, $2,720.00, $2,720.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

TRIP4/ASC1, Peptide - MBS427783 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

TRIP4/ASC1, Peptide - MBS428448 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Dog, Pig, Bovine

ASC1 Protein - NBP1-89656PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

ASC-1 Blocking Peptide - abx061225 from Abbexa Category Peptide Species Human, Monkey

TRIP4 Peptide, Human - M34GP16644H from Creative Peptides Category Peptide Source Synthetic. Species Human

ASC-1 Blocking Peptide - CBP5138 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey

TRIP4 peptide - orb319284 from Biorbyt Category Peptide Prices $247.00, $510.00 Sizes 1 mg, 5 mg

ASC1 Recombinant Protein Antigen - NBP2-58194PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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