SKA1

Gene Symbol SKA1
Entrez Gene 220134
Alt Symbol C18orf24
Species Human
Gene Type protein-coding
Description spindle and kinetochore associated complex subunit 1
Other Description spindle and KT (kinetochore) associated 1|spindle and kinetochore-associated protein 1
Swissprots B4E0P4 B2R9Y6 Q96BD8
Accessions EAW62971 EAW62972 EAW62973 Q96BD8 AK303464 BAG64506 AK313968 BAG36683 BC005972 BC015606 BC015706 AAH15706 BG493245 BM470268 BQ069178 BU659790 BX956145 CN403719 NM_001039535 NP_001034624 NM_145060 NP_659497
Function Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules. {ECO:0000269|PubMed:17093495, ECO:0000269|PubMed:19289083}.
Subcellular Location Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins. Associates with kinetochores following microtubule attachment from prometaphase, through mid- anaphase and then vanishes in telophase.

Anti-SKA1 antibody - ab118586 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-SKA1 antibody (ab118586) at 0.5 µg/mlLane 2 : Anti-SKA1 antibody (ab118586) at 1 µg/mlLane 1 : A549 cell lysateLane 2 : A549 cell lysate

Anti-SKA1 antibody - ab91550 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-SKA1 antibody (ab91550) at 0.5 µg/mlLane 2 : Anti-SKA1 antibody (ab91550) at 1 µg/mlLane 1 : A549 cell lysateLane 2 : A549 cell lysateLysates/proteins at 15 µg per lane.

Anti-SKA1 Antibody (aa51-100) - LS-C146354 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SKA1 antibody LS-C146354 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.

Anti-SKA1 Antibody (C-Terminus) IHC-plus™ - LS-B5037 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SKA1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5037 concentration 5 ug/ml.

SKA1 Antibody - NBP1-72131 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SKA1 Antibody [NBP1-72131] - Analysis of anti-SKA1 antibody with human brain, cerebellum at concentration 5 ug/ml.

SKA1 Antibody - NBP1-92391 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SKA1 Antibody - NBP2-20376 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: SKA1 Antibody [NBP2-20376] - Paraffin-embedded mouse liver. C18orf24 antibody diluted at 1:500.

SKA1 Polyclonal Antibody - bs-7846R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SKA1 antibody produced in rabbit - SAB3500101 from Sigma-Aldrich

Prices $316.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SKA1: <B>Cat. No. SAB3500101</B>: SKA1 in A549 cell lysate with SKA1 antibody at (A) 0.5 and (B) 1 μg/mL.

Anti-SKA1 antibody produced in rabbit - SAB2701430 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SKA1: <B>Cat. No. SAB2701430</B>: Immunohistochemical analysis of paraffin-embedded Gastric carcinoma, using C18orf24 antibody at 1:500 dilution.

C18orf24 antibody - GTX119803 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-C18orf24 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX119803

SKA1 antibody - orb101213 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Line graph illustrates about the Ag-Ab reactions using different concentrations of antigen and serial dilutions of SKA1 antibody

SKA1 antibody - orb75276 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of A549 cell lysate at (A) 0.5 and (B) 1 ug/mL using SKA1 antibody

SKA1 (C-term) antibody - AP23902PU-N from Acris Antibodies

Prices $430.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

SKA1 antibody - AP30787PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of SKA1 in A549 cell lysate with SKA1 antibody at 0.5 µg/ml (A) and 1 μg/ml (B).

SKA1 antibody - H00220134-B01P from Acris Antibodies

Prices $1,530.00
Sizes 500 µg
Host Mouse
Clonality Polyclonal

SKA1 Antibody - 5401 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of SKA1 in A549 cell lysate with SKA1 antibody at (A) 0.5 and (B) 1 μg/mL.

SKA1 Antibody - 254143 from ABBIOTEC

Prices $292.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

SKA1 Antibody - 24970 from Signalway Antibody

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of SKA1 in A549 cell lysate with SKA1 antibody at (A) 0.5 and (B) 1 ug/mL.

Anti-SKA1 (C-terminal) polyclonal antibody - DPABH-10011 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-SKA1 (aa 100-200) polyclonal antibody - DPABH-16014 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-SKA1 (C-terminal) polyclonal antibody - DPAB-L21127 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

SKA1 Polyclonal Antibody - PA5-20817 from Thermo Fisher Scientific

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of A549 cell lysate using a SKA1 polyclonal antibody (Product # PA5-20817) at (A) 0.5 and (B) 1 ug/mL.

SKA1, Polyclonal Antibody - MBS150085 from MyBioSource

Prices $140.00, $355.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
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