SKA1

Gene Symbol	SKA1
Entrez Gene	220134
Alt Symbol	C18orf24
Species	Human
Gene Type	protein-coding
Description	spindle and kinetochore associated complex subunit 1
Other Description	spindle and KT (kinetochore) associated 1|spindle and kinetochore-associated protein 1
Swissprots	B4E0P4 B2R9Y6 Q96BD8
Accessions	EAW62971 EAW62972 EAW62973 Q96BD8 AK303464 BAG64506 AK313968 BAG36683 BC005972 BC015606 BC015706 AAH15706 BG493245 BM470268 BQ069178 BU659790 BX956145 CN403719 NM_001039535 NP_001034624 NM_145060 NP_659497
Function	Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules. {ECO:0000269|PubMed:17093495, ECO:0000269|PubMed:19289083}.
Subcellular Location	Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins. Associates with kinetochores following microtubule attachment from prometaphase, through mid- anaphase and then vanishes in telophase.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SKA1 full length protein - ab177610 from Abcam Category Protein Source E. coli Species Human

Human SKA1 peptide - ab46824 from Abcam Category Peptide

Human SKA1 peptide - ab46825 from Abcam Category Peptide

SKA1 Antibody Blocking Peptide - LS-E30778 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SKA1 Antibody Blocking Peptide - LS-E20044 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SKA1 Peptide - NBP1-76313PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

C18orf24-Antibody-C-term-Blocking-peptide - BP12001b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SKA1 protein (His tag) - 80R-3729 from Fitzgerald Category Protein Prices $275.00 Sizes 10 µg Source E.coli

SKA1 (1-255, His-tag) - AR51416PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 50 µg Source E. coli Species Human

SKA1 (1-255, His-tag) - AR51416PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source E. coli Species Human

SKA1 Control Peptide - AP30787CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SKA1, 1-255aa Human, His tag, E.coli - 01-P2596 from ARP American Research Products Category Protein Prices $159.00, $369.00, $849.00 Sizes 2 µg, 10 µg, 50 µg Species Human

SKA1 Peptide - 5401P from ProSci Category Peptide Species Human

SKA1, 1-255aa Human, His tag, E.coli - GWB-ATG0C6 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 10 μg, 50 μg Source E.coli Species Human

Recombinant Human SKA1, His-tagged - SKA1-5100H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human spindle and kinetochore associated complex subunit 1, His-tagged - SKA1-499H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human SKA1 - SKA1-1350H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human Spindle and kinetochore-associated protein 1(SKA1) - CSB-YP846589HU CSB-EP846589HU CSB-BP846589HU CSB-MP846589HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SKA1, 1-255aa, Human, His tag, E.coli - ATGP2596 from ATGen Category Protein Prices $240.00, $720.00 Sizes 10 µg, 50 µg Species Human

Spindle And Kinetochore Associated Complex Subunit 1 Protein (Recombinant) - abx263411 from Abbexa Category Protein

SKA1 (transcript variant 2) - TP302370 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SKA1 (transcript variant 1) - TP321913 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SKA1 Protein - NBP1-92391PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

Human SKA1 protein - orb260098 from Biorbyt Category Protein Prices $230.00, $442.00, $1,811.00 Sizes 1 μg, 5 μg, 50 μg Species Human

SKA1 Peptide, Human - M34GP14282H from Creative Peptides Category Peptide Source Synthetic. Species Human

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