CHMP6

Gene Symbol	CHMP6
Entrez Gene	79643
Alt Symbol	VPS20
Species	Human
Gene Type	protein-coding
Description	charged multivesicular body protein 6
Other Description	chromatin modifying protein 6|chromatin-modifying protein 6|hVps20|vacuolar protein sorting-associated protein 20
Swissprots	A8K7U0 Q96FZ7 Q53FU4 Q9HAE8
Accessions	EAW89622 Q96FZ7 AK021811 BAB13901 AK223187 BAD96907 AK292105 BAF84794 AY329087 AAQ91196 BC010108 AAH10108 BP196406 CR457284 CAG33565 HQ448670 ADQ33148 XM_005257668 XP_005257725 NM_024591 NP_078867
Function	Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities,
Subcellular Location	Endomembrane system. Endosome membrane; Lipid-anchor. Late endosome membrane {ECO:0000305}. Note=Localizes to endosomal membranes.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:15511219}.
Top Pathways	Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CHMP6 full length protein - ab124606 from Abcam Category Protein Source E. coli Species Human

Human CHMP6 peptide - ab90851 from Abcam Category Peptide

CHMP6 Antibody Blocking Peptide - LS-E1687 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHMP6 Antibody Blocking Peptide - LS-E23852 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CHMP6 Recombinant Protein - H00079643-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human CHMP6 Protein - NBP1-99015 from Novus Biologicals Category Protein Prices $269.00, $729.00 Sizes 100 µg, 500 µg Source E. coli Species Human

CHMP6-Antibody-N-term-Blocking-peptide - BP12454a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human CHMP6 protein - orb168116 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

CHMP6 protein (His tag) - 80R-2252 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

CHMP6 (1-201, His-tag) - AR50335PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

CHMP6 (1-201, His-tag) - AR50335PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

CHMP6 - H00079643-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CHMP6 - H00079643-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CHMP6, 1-201aa, Human, His tag, E.coli - 01-P1511 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

CHMP6 fusion protein - ag9357 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

CHMP6, 1-201aa , Human, His tag, E.coli - GWB-P0527G from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human CHMP6, His-tagged - CHMP6-27071TH from Creative Biomart Category Protein Source E. coli

Recombinant Human Charged Multivesicular Body Protein 6, His-tagged - CHMP6-5589H from Creative Biomart Category Protein

Recombinant Human CHMP6, His-tagged - CHMP6-15851H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Charged multivesicular body protein 6(CHMP6) - CSB-YP846622HU CSB-EP846622HU CSB-BP846622HU CSB-MP846622HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CHMP6, 1-201aa, Human, His tag, E.coli - ATGP1511 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

CHMP6 Recombinant Protein Antigen - NBP1-83727PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CHMP6 Recombinant Protein Antigen - NBP1-83726PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CHMP6 Peptide, Human - M34GP03109H from Creative Peptides Category Peptide Source Synthetic. Species Human

CHMP6 - PAT-81551-1 from Nordic BioSite Category Protein Species Human

Search more