Gene Symbol | ECM1 |
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Entrez Gene | 1893 |
Alt Symbol | URBWD |
Species | Human |
Gene Type | protein-coding |
Description | extracellular matrix protein 1 |
Other Description | secretory component p85 |
Swissprots | A8K8S0 Q8IZ60 Q5T5G5 Q5T5G6 Q5T5G4 Q16610 O43266 B4DW49 B4DY60 |
Accessions | AAB05934 ACV13189 EAW53544 EAW53545 EAW53546 EAW53547 Q16610 AK097046 BAG53412 AK097205 AK292435 BAF85124 AK301369 BAG62911 AK302279 BAG63622 AK316390 BAH14761 BC023505 AAH23505 CA413352 DA963826 DQ010946 AAY57437 DQ112074 ABA29445 DQ893011 ABM83937 DQ896257 ABM87256 U65932 AAB05933 U68186 AAB88081 U68187 AAB88082 NM_001202858 NP_001189787 NM_004425 NP_004416 NM_022664 NP_073155 |
Function | Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. {ECO:0000269|PubMed:11165938, ECO:0000269|PubMed:11292659, ECO:0000269|PubMed:16512877}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expressed in breast cancer tissues. Little or no expression observed in normal breast tissues. Expressed in skin; wide expression is observed throughout the dermis with minimal expression in the epidermis. {ECO:0000269|PubMed:11292659, ECO:0000269|PubMed:12604605}. |
ECM1 (C-12) - sc-365946 from Santa Cruz Biotechnology
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ECM1 (F-1) - sc-365335 from Santa Cruz Biotechnology
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ECM1 (H-300) - sc-135032 from Santa Cruz Biotechnology
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ECM1 (N-17) - sc-65086 from Santa Cruz Biotechnology
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ECM1 (P-19) - sc-65087 from Santa Cruz Biotechnology
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ECM1 (Q-19) - sc-65088 from Santa Cruz Biotechnology
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Anti-Secretory Component Glycoprotein antibody [0.N.556] - ab17377 from Abcam
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Anti-Secretory Component Glycoprotein antibody [COMPO2], prediluted - ab75232 from Abcam
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Anti-Secretory Component Glycoprotein antibody [EPR6701] - ab126629 from Abcam
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Anti-Secretory Component Glycoprotein antibody [SC-05] - ab3924 from Abcam
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Anti-Secretory Component Glycoprotein antibody [SPM217] - ab17921 from Abcam
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Anti-ECM1 Antibody - LS-C335162 from LifeSpan Bioscience
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Anti-ECM1 Antibody (aa153-202) - LS-C201513 from LifeSpan Bioscience
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Anti-ECM1 Antibody (Internal, clone EPR6701) - LS-C152264 from LifeSpan Bioscience
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Anti-ECM1 Antibody - LS-C146983 from LifeSpan Bioscience
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Anti-ECM1 Antibody (clone SC-05) - LS-C122408 from LifeSpan Bioscience
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Anti-ECM1 Antibody (clone SPM301) - LS-C189194 from LifeSpan Bioscience
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Anti-ECM1 Antibody (aa546) - LS-C190196 from LifeSpan Bioscience
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ECM-1/Secretory Component P85 Antibody (SC05) - NBP2-29464 from Novus Biologicals
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ECM-1/Secretory Component P85 Antibody [Unconjugated] - AF3937 from Novus Biologicals
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ECM-1/Secretory Component P85 Antibody (SPM217) - NBP2-32869 from Novus Biologicals
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ECM-1/Secretory Component P85 Antibody - NBP1-87449 from Novus Biologicals
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ECM-1/Secretory Component P85 Antibody [Biotin] - BAF3937 from Novus Biologicals
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ECM-1/Secretory Component P85 Antibody (SC05) [DyLight 405LS] - NBP2-33086V3 from Novus Biologicals
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ECM-1/Secretory Component P85 Antibody (SC05) [7C] - NBP2-33086V2 from Novus Biologicals
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