NCOA6

Gene Symbol	NCOA6
Entrez Gene	23054
Alt Symbol	AIB3, ASC2, NRC, PRIP, RAP250, TRBP
Species	Human
Gene Type	protein-coding
Description	nuclear receptor coactivator 6
Other Description	NRC RAP250|PPAR-interacting protein|activating signal cointegrator 2|activating signal cointegrator-2|amplified in breast cancer protein 3|amplified in breast cancer-3 protein|cancer-amplified transcriptional coactivator ASC-2|nuclear receptor coactivator RAP250|nuclear receptor-activating protein, 250 kDa|peroxisome proliferator-activated receptor interacting protein|peroxisome proliferator-activated receptor-interacting protein|thyroid hormone receptor binding protein|thyroid hormone receptor-binding protein
Swissprots	Q9NTZ9 Q14686 E1P5P7 A6NLF1 Q9UH74 B2RMN5 Q9UK86
Accessions	EAW76254 EAW76255 Q14686 AF128458 AAF37003 AF171667 AAF71829 AF177388 AAF13595 AF208227 AAF16403 AF245115 AAF78480 AI498955 AK027040 BC035676 BC047886 BC069829 BC114613 AAI14614 BC136272 AAI36273 BU187688 D80003 BAA11498 JF707637 AEG79564 JF707638 AEG79565 JF707639 AEG79566 L37706 XM_006723755 XP_006723818 XM_011528721 XP_011527023 XM_011528722 XP_011527024 XM_011528723 XP_011527025 XM_011528724 XP_011527026 XM_011528725 XP_011527027 XM_011528726 XP_011527028 XM_011528727 XP_011527029 XM_011528728 XP_011527030 XM_011528729 XP_011527031 XM_011528730 XP_011527032 XM_011528731 XP_011527033 XM_011528732 XP_011527034 XM_011528733 XP_011527035 XM_011528734 XP_011527036 XM_011528735 XP_011527037 XR_936514 XR_936515 NM_001242539 NP_001229468 NM_014071 NP_054790
Function	Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Coactivates expression in an agonist- and AF2-dependent manner. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ERs), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Probably functions as a general coactivator, rather than just a nuclear receptor coactivator. May also be involved in the coactivation of the NF-kappa-B pathway. May coactivate expression via a remodeling of chromatin and its interaction with histone acetyltransferase proteins.
Subcellular Location	Nucleus.
Tissue Specificity	Ubiquitous. Highly expressed in brain, prostate, testis and ovary; weakly expressed in lung, thymus and small intestine.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ASC-2 peptide - ab19344 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human ASC-2 protein fragment - ab161520 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Recombinant Human NCOA6 Protein - H00023054-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NCOA-6 - H00023054-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NCOA-6 - H00023054-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NCOA6 fusion protein - Ag18880 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

NCOA6 fusion protein - ag18737 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Nuclear receptor coactivator 6(NCOA6) ,partial - CSB-YP015545HU CSB-EP015545HU CSB-BP015545HU CSB-MP015545HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NCOA6 Recombinant Protein Antigen - NBP1-89193PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NCOA6 Peptide, Human - M34GP10199H from Creative Peptides Category Peptide Source Synthetic. Species Human

NCOA6 Recombinant Protein Antigen - NBP2-55622PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Nuclear receptor coactivator 6 (NCOA6), partial, Recombinant Protein - MBS1354562 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more