Gene Symbol | MUM1 |
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Entrez Gene | 84939 |
Alt Symbol | EXPAND1, HSPC211, MUM-1 |
Species | Human |
Gene Type | protein-coding |
Description | melanoma associated antigen (mutated) 1 |
Other Description | PWWP domain-containing protein MUM1|melanoma ubiquitous mutated protein|mutated melanoma-associated antigen 1|protein expandere |
Swissprots | A1L489 B5ME02 Q8N2I4 J3KQD6 Q2TAK8 B7ZLY8 Q5XKB9 Q13109 Q96A67 |
Accessions | AAC50238 EAW69509 EAW69511 EAW69512 EAW69513 EAW69514 Q2TAK8 AF151045 AAF36131 AK025936 BAB15287 AK027774 BAB55357 AK075241 BAC11493 AK309092 AK310721 AL360266 CAB96179 BC001806 BC008098 AAH08098 BC019585 BC021016 BC082987 AAH82987 BC110874 AAI10875 BC130443 AAI30444 BC144138 AAI44139 BC144147 BG723598 BI553935 BQ071619 BQ895780 BU541563 BU741593 CR457395 CAG33676 DA739708 DN993266 U20896 AAC50239 U20897 AAC50240 XM_011528380 XP_011526682 XM_011528381 XP_011526683 XM_011528382 XP_011526684 XM_011528383 XP_011526685 XM_011528384 XP_011526686 XM_011528385 XP_011526687 NM_032853 NP_116242 NR_024247 |
Function | Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. {ECO:0000269|PubMed:20347427}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:20347427}. Note=Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1. |
EXPAND1/MUM1 (D1Z6Y) Rabbit mAb - 13437 from Cell Signaling Technology
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MUM1 (D-11) - sc-514332 from Santa Cruz Biotechnology
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MUM1 (C-13) - sc-139009 from Santa Cruz Biotechnology
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MUM1 (H-43) - sc-382234 from Santa Cruz Biotechnology
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MUM1 (N-18) - sc-139011 from Santa Cruz Biotechnology
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Anti-MUM1 antibody - ab118808 from Abcam
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Anti-MUM1 antibody - ab69220 from Abcam
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Anti-MUM1 antibody [4G10] - ab98957 from Abcam
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Anti-MUM1 antibody - C-terminal - ab173693 from Abcam
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MUM1 Antibody - NBP1-78760 from Novus Biologicals
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MUM1 Polyclonal Antibody - bs-6811R from Bioss
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ANTI-MUM1 (C-TERM) antibody produced in rabbit - SAB1304318 from Sigma-Aldrich
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Monoclonal Anti-MUM1 antibody produced in mouse - SAB5300048 from Sigma-Aldrich
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Anti-MUM1 antibody produced in rabbit - HPA048063 from Sigma-Aldrich
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Anti-MUM1 antibody produced in mouse - SAB1408139 from Sigma-Aldrich
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MUM1-Antibody-C-term - AP17700b from Abgent, a WuXi AppTec company
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EGR1-Antibody - AO1382a from Abgent, a WuXi AppTec company
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MUM1 Antibody - C-terminal region (OAAB13131) - OAAB13131 from Aviva Systems Biology
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MUM1 antibody - orb224929 from Biorbyt
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MUM1 antibody - 10R-2189 from Fitzgerald
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MUM1 antibody - orb100374 from Biorbyt
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MUM1 antibody - 12682-1-AP from Acris Antibodies
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MUM1 antibody - AM06446SU-N from Acris Antibodies
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MUM1 antibody - AM20464SU-N from Acris Antibodies
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Mouse Anti-Human MUM1 - 119-14217 from RayBiotech
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