Gene Symbol | MUM1 |
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Entrez Gene | 84939 |
Alt Symbol | EXPAND1, HSPC211, MUM-1 |
Species | Human |
Gene Type | protein-coding |
Description | melanoma associated antigen (mutated) 1 |
Other Description | PWWP domain-containing protein MUM1|melanoma ubiquitous mutated protein|mutated melanoma-associated antigen 1|protein expandere |
Swissprots | A1L489 B5ME02 Q8N2I4 J3KQD6 Q2TAK8 B7ZLY8 Q5XKB9 Q13109 Q96A67 |
Accessions | AAC50238 EAW69509 EAW69511 EAW69512 EAW69513 EAW69514 Q2TAK8 AF151045 AAF36131 AK025936 BAB15287 AK027774 BAB55357 AK075241 BAC11493 AK309092 AK310721 AL360266 CAB96179 BC001806 BC008098 AAH08098 BC019585 BC021016 BC082987 AAH82987 BC110874 AAI10875 BC130443 AAI30444 BC144138 AAI44139 BC144147 BG723598 BI553935 BQ071619 BQ895780 BU541563 BU741593 CR457395 CAG33676 DA739708 DN993266 U20896 AAC50239 U20897 AAC50240 XM_011528380 XP_011526682 XM_011528381 XP_011526683 XM_011528382 XP_011526684 XM_011528383 XP_011526685 XM_011528384 XP_011526686 XM_011528385 XP_011526687 NM_032853 NP_116242 NR_024247 |
Function | Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage. {ECO:0000269|PubMed:20347427}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:20347427}. Note=Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1. |
MUM1-Antibody-C-term-Blocking-Peptide - BP17700b from Abgent, a WuXi AppTec company
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MUM1 fusion protein - Ag3371 from Proteintech Group
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Recombinant Human MUM1, GST-tagged - MUM1-1112H from Creative Biomart
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Recombinant Human PWWP domain-containing protein MUM1(MUM1) - CSB-YP648777HU CSB-EP648777HU CSB-BP648777HU CSB-MP648777HU from Cusabio
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MUM-1 (261-269) - C08166 from Creative Peptides
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MUM1 Blocking Peptide - CBP7455 from Cohesion Biosciences
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PWWP domain-containing protein MUM1 (MUM1), Recombinant Protein - MBS1401639 from MyBioSource
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MUM1 peptide - orb382360 from Biorbyt
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