SLC51B
| Gene Symbol | SLC51B |
|---|---|
| Entrez Gene | 123264 |
| Alt Symbol | OSTB, OSTBETA |
| Species | Human |
| Gene Type | protein-coding |
| Description | solute carrier family 51, beta subunit |
| Other Description | OST-beta|organic solute transporter beta subunit|organic solute transporter subunit beta|solute carrier family 51 subunit beta |
| Swissprots | Q3SYF5 Q86UW2 |
| Accessions | EAW77708 Q86UW2 AA156136 AA621440 AI793107 AK129601 AY194242 AAP23992 BC103842 AAI03843 BC103843 AAI03844 BC103844 AAI03845 XM_005254159 XP_005254216 NM_178859 NP_849190 |
| Function | Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Modulates SLC51A glycosylation, membrane trafficking and stability activities. {ECO:0000269|PubMed:16317684}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}; Single-pass membrane protein {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}. Note=Mainly restricted to the lateral and basal membranes of ileal enterocytes. |
| Tissue Specificity | Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat. {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}. |
| Top Pathways | Bile secretion |
Anti-OST-beta antibody - ab121285 from Abcam
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OSTB Antibody - NBP1-91108 from Novus Biologicals
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OST-beta Polyclonal Antibody - bs-2128R from Bioss
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Anti-SLC51B antibody produced in rabbit - HPA008533 from Sigma-Aldrich
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OST-beta Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-2128R-A350 from Bioss
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OST-beta Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-2128R-A488 from Bioss
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OST-beta Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-2128R-A555 from Bioss
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OST-beta Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-2128R-A647 from Bioss
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OST-beta Polyclonal Antibody, Cy3 Conjugated - bs-2128R-Cy3 from Bioss
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OST-beta Polyclonal Antibody, Cy5 Conjugated - bs-2128R-Cy5 from Bioss
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OST-beta Polyclonal Antibody, Cy5.5 Conjugated - bs-2128R-Cy5.5 from Bioss
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OST-beta Polyclonal Antibody, Cy7 Conjugated - bs-2128R-Cy7 from Bioss
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OST-beta Polyclonal Antibody, FITC Conjugated - bs-2128R-FITC from Bioss
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Rabbit Anti-OST-beta Polyclonal Antibody, PE Conjugated - bs-2128R-PE from Bioss
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OST-beta Polyclonal Antibody, Biotin Conjugated - bs-2128R-Biotin from Bioss
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OST-beta Polyclonal Antibody, HRP Conjugated - bs-2128R-HRP from Bioss
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Anti-SLC51B (aa 77-127) polyclonal antibody - DPABH-16402 from Creative Diagnostics
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OST-beta Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated - bs-2128R-A594 from Bioss
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OST beta antibody - orb1964 from Biorbyt
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SLC51B Antibody,Biotin conjugated - CSB-PA771440LD01HU from Cusabio
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SLC51B Antibody,FITC conjugated - CSB-PA771440LC01HU from Cusabio
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SLC51B Antibody,HRP conjugated - CSB-PA771440LB01HU from Cusabio
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SLC51B Antibody - CSB-PA771440LA01HU from Cusabio
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OST-beta Polyclonal Antibody, ALEXA FLUOR® 680 Conjugated - bs-2128R-A680 from Bioss
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OST-beta Polyclonal Antibody, ALEXA FLUOR® 750 Conjugated - bs-2128R-A750 from Bioss
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