SLC51B

Gene Symbol	SLC51B
Entrez Gene	123264
Alt Symbol	OSTB, OSTBETA
Species	Human
Gene Type	protein-coding
Description	solute carrier family 51, beta subunit
Other Description	OST-beta|organic solute transporter beta subunit|organic solute transporter subunit beta|solute carrier family 51 subunit beta
Swissprots	Q3SYF5 Q86UW2
Accessions	EAW77708 Q86UW2 AA156136 AA621440 AI793107 AK129601 AY194242 AAP23992 BC103842 AAI03843 BC103843 AAI03844 BC103844 AAI03845 XM_005254159 XP_005254216 NM_178859 NP_849190
Function	Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Modulates SLC51A glycosylation, membrane trafficking and stability activities. {ECO:0000269|PubMed:16317684}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}; Single-pass membrane protein {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}. Note=Mainly restricted to the lateral and basal membranes of ileal enterocytes.
Tissue Specificity	Widely expressed with a high expression in ileum. Expressed in testis, colon, liver, small intestine, kidney, ovary and adrenal gland; and at low levels in heart, lung, brain, pituitary, thyroid gland, uterus, prostate, mammary gland and fat. {ECO:0000269|PubMed:12719432, ECO:0000269|PubMed:16317684}.
Top Pathways	Bile secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human OST-beta protein fragment - ab171468 from Abcam Category Protein Source E. coli Species Human

Recombinant Human OSTB Protein - NBP2-22816 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

SLC51B protein (His tag) - 80R-3499 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

SLC51B (57-128, His-tag) - AR51189PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

SLC51B (57-128, His-tag) - AR51189PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

SLC51B, 57-128aa, Human, His tag, E.coli - 01-P2366 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

OSTbeta fusion protein - ag16953 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

OSTbeta fusion protein - Ag15751 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human solute carrier family 51, beta subunit, His-tagged - SLC51B-283H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Organic solute transporter subunit beta(OSTB) - CSB-YP771440HU CSB-EP771440HU CSB-BP771440HU CSB-MP771440HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SLC51B, 57-128aa, Human, His tag, E.coli - ATGP2366 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

Organic solute transporter beta (OSTbeta) - TP317638 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Human SLC51B protein - orb260097 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

OSTB Protein - NBP1-91108PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

SLC51B Peptide, Human - M34GP14607H from Creative Peptides Category Peptide Source Synthetic. Species Human

SLC51B - PAT-82365-1 from Nordic BioSite Category Protein Species Human

SLC51B - PAT-82365-2 from Nordic BioSite Category Protein Species Human

Organic solute transporter subunit beta (ostb), Recombinant Protein - MBS1450523 from MyBioSource Category Protein Prices $770.00, $770.00, $995.00, $995.00, $1,060.00, $1,060.00, $1,520.00, $1,520.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

SLC51B, Recombinant Protein - MBS205305 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 50 µg, 250 µg Source E Coli Species Human

Solute Carrier Family 51 Beta, Recombinant Protein - MBS146390 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

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