Gene Symbol | FA2H |
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Entrez Gene | 79152 |
Alt Symbol | FAAH, FAH1, FAXDC1, SCS7, SPG35 |
Species | Human |
Gene Type | protein-coding |
Description | fatty acid 2-hydroxylase |
Other Description | fatty acid alpha-hydroxylase|fatty acid hydroxylase domain containing 1|spastic paraplegia 35 (autosomal recessive) |
Swissprots | O75213 Q9H1A5 B7Z8T6 Q96DK1 Q7L5A8 |
Accessions | AAC23496 EAW95677 EAW95678 Q7L5A8 AA857184 AJ278219 CAC20436 AK058016 BAB71632 AK303878 BAH14072 AK315512 BAG37893 BC002679 AAH02679 BC004263 AAH04263 BC010453 BC017049 AAH17049 DA890369 XM_011523317 XP_011521619 XM_011523318 XP_011521620 XM_011523319 XP_011521621 NM_024306 NP_077282 |
Function | Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids. {ECO:0000269|PubMed:15337768, ECO:0000269|PubMed:17355976}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15337768}; Multi-pass membrane protein {ECO:0000269|PubMed:15337768}. Microsome membrane {ECO:0000269|PubMed:15337768}; Multi-pass membrane protein {ECO:0000269|PubMed:15337768}. |
Tissue Specificity | Detected in differentiating cultured keratinocytes (at protein level). Detected in epidermis and cultured keratinocytes. Highly expressed in brain and colon. Detected at lower levels in testis, prostate, pancreas and kidney. {ECO:0000269|PubMed:15337768, ECO:0000269|PubMed:17355976}. |
Human FA2H full length protein - ab163991 from Abcam
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FA2H / FAAH Antibody Blocking Peptide - LS-E7596 from LifeSpan Bioscience
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FA2H / FAAH Antibody Blocking Peptide - LS-E11673 from LifeSpan Bioscience
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FAAH Antibody Blocking Peptide - LS-E4680 from LifeSpan Bioscience
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FAAH Antibody Blocking Peptide - LS-E26842 from LifeSpan Bioscience
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Recombinant Human FAAH Protein - H00002166-Q01 from Novus Biologicals
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Recombinant Human FA2H Protein - H00079152-P01 from Novus Biologicals
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FA2H-Antibody-Center-Blocking-Peptide - BP4799c from Abgent, a WuXi AppTec company
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Fa2h Blocking Peptide - 33R-3743 from Fitzgerald
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Fatty acid alpha-hydroxylase - H00079152-P01-10 from Acris Antibodies
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Fatty acid alpha-hydroxylase - H00079152-P01-25 from Acris Antibodies
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FA2H fusion protein - Ag7717 from Proteintech Group
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FA2H fusion protein - Ag7956 from Proteintech Group
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Recombinant Human FA2H, MYC/DDK-tagged - FA2H-891H from Creative Biomart
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Recombinant Human FA2H, GST-tagged - FA2H-893H from Creative Biomart
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Recombinant Human FA2H, His-tagged - FA2H-12628H from Creative Biomart
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Fatty acid alpha-hydroxylase - TP302093 from Acris Antibodies
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FA2H Protein - NBP2-37957PEP from Novus Biologicals
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FAAH Recombinant Protein Antigen - NBP1-83937PEP from Novus Biologicals
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FA2H Peptide, Human - M34GP05182H from Creative Peptides
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FAAH Peptide, Human - M34GP05183H from Creative Peptides
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Fatty acid 2-hydroxylase (FA2H), Recombinant Protein - MBS7014458 from MyBioSource
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FAAH peptide - orb13160 from Biorbyt
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FA2H Recombinant Protein Antigen - NBP2-58016PEP from Novus Biologicals
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