Gene Symbol | FA2H |
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Entrez Gene | 79152 |
Alt Symbol | FAAH, FAH1, FAXDC1, SCS7, SPG35 |
Species | Human |
Gene Type | protein-coding |
Description | fatty acid 2-hydroxylase |
Other Description | fatty acid alpha-hydroxylase|fatty acid hydroxylase domain containing 1|spastic paraplegia 35 (autosomal recessive) |
Swissprots | O75213 Q9H1A5 B7Z8T6 Q96DK1 Q7L5A8 |
Accessions | AAC23496 EAW95677 EAW95678 Q7L5A8 AA857184 AJ278219 CAC20436 AK058016 BAB71632 AK303878 BAH14072 AK315512 BAG37893 BC002679 AAH02679 BC004263 AAH04263 BC010453 BC017049 AAH17049 DA890369 XM_011523317 XP_011521619 XM_011523318 XP_011521620 XM_011523319 XP_011521621 NM_024306 NP_077282 |
Function | Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids. {ECO:0000269|PubMed:15337768, ECO:0000269|PubMed:17355976}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15337768}; Multi-pass membrane protein {ECO:0000269|PubMed:15337768}. Microsome membrane {ECO:0000269|PubMed:15337768}; Multi-pass membrane protein {ECO:0000269|PubMed:15337768}. |
Tissue Specificity | Detected in differentiating cultured keratinocytes (at protein level). Detected in epidermis and cultured keratinocytes. Highly expressed in brain and colon. Detected at lower levels in testis, prostate, pancreas and kidney. {ECO:0000269|PubMed:15337768, ECO:0000269|PubMed:17355976}. |
FA2H (A-12) - sc-161044 from Santa Cruz Biotechnology
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FA2H (G-15) - sc-161045 from Santa Cruz Biotechnology
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FA2H (H-143) - sc-367255 from Santa Cruz Biotechnology
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Anti-FA2H antibody - ab175093 from Abcam
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Anti-FA2H antibody - ab68902 from Abcam
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Anti-FA2H antibody [2E3] - ab170421 from Abcam
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Anti-FA2H / FAAH Antibody - LS-C26835 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa127-157, AP) - LS-C222484 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa127-157, APC) - LS-C222485 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa127-157, Biotin) - LS-C222486 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa127-157, FITC) - LS-C222487 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa257-306) - LS-C134951 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa127-157, PE) - LS-C222489 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa127-157, Azide-free, HRP) - LS-C222488 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody - LS-C307951 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa127-157) - LS-C329530 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (clone 1B5) - LS-C174833 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (clone 1C5) - LS-C338204 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (clone 2E3) - LS-C174828 from LifeSpan Bioscience
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Anti-FA2H / FAAH Antibody (aa121-148) - LS-C167898 from LifeSpan Bioscience
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FAAH Antibody - NBP1-83937 from Novus Biologicals
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FA2H Antibody - NBP2-37957 from Novus Biologicals
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FA2H Antibody - H00079152-B01P from Novus Biologicals
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Anti-FA2H (66-80) antibody produced in rabbit - SAB1102029 from Sigma-Aldrich
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FA2H Antibody - middle region (OAAB02216) - OAAB02216 from Aviva Systems Biology
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