MED23

Gene Symbol MED23
Entrez Gene 9439
Alt Symbol ARC130, CRSP130, CRSP133, CRSP3, DRIP130, MRT18, SUR-2, SUR2
Species Human
Gene Type protein-coding
Description mediator complex subunit 23
Other Description 130 kDa transcriptional co-activator|133 kDa transcriptional co-activator|activator-recruited cofactor 130 kDa component|cofactor required for Sp1 transcriptional activation subunit 3|mediator of RNA polymerase II transcription subunit 23|vitamin D3 receptor interacting protein
Swissprots Q9NTU0 Q5JWT3 Q6P9H6 Q5JWT4 B9TX55 Q9NTT9 Q9Y667 Q9ULK4 Q9Y5P7 O95403 Q9H0J2
Accessions EAW48049 EAW48050 EAW48051 EAW48052 Q9ULK4 AB033042 BAA86530 AF104255 AAD12724 AF105332 AAD31729 AF135022 AAD30202 AI249380 AJ420587 AK304711 BAG65476 AK315030 AL136776 CAB66710 AM393572 CAL38449 AW295188 BC007088 AAH07088 BC060759 AAH60759 DB453121 EU392520 ACB88848 EU392521 ACB88849 EU392522 ACB88850 EU392523 ACB88851 EU392524 ACB88852 EU392525 ACB88853 EU392526 ACB88854 EU392527 ACB88855 EU392528 ACB88856 EU392529 ACB88857 EU392530 ACB88858 EU392531 ACB88859 EU392532 ACB88860 EU832308 ACE87565 EU832392 ACE86877 XM_005267223 XP_005267280 XM_006715612 XP_006715675 XM_011536257 XP_011534559 NM_001270521 NP_001257450 NM_001270522 NP_001257451 NM_004830 NP_004821 NM_015979 NP_057063
Function Required for transcriptional activation subsequent to the assembly of the preinitiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling. {ECO:0000250, ECO:0000269|PubMed:10353252, ECO:0000269|PubMed:14759369, ECO:0000269|PubMed:16595664}.
Subcellular Location Nucleus {ECO:0000305}.

CRSP130 (E-19) - sc-12454 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CRSP130 (E-19): sc-12454. Western blot analysis of CRSP130 expression in HeLa nuclear extract (A) and PC-3 whole cell lysate (B).

Anti-DRIP130 antibody - ab196752 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-DRIP130 antibody (ab196752) at 1/500 dilutionLane 1 : A549 cell extractsLane 2 : A549 cell extracts with Immunizing peptide

Anti-MED23 / SUR2 Antibody (aa1-50) - LS-C79472 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MED23 / SUR2 Antibody - LS-C183814 from LifeSpan Bioscience

Prices $740.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-MED23 / SUR2 Antibody (C-Terminus) - LS-C79474 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MED23 / SUR2 Antibody (aa400-450) - LS-C79473 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MED23 / SUR2 Antibody (Biotin) - LS-C183815 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MED23 / SUR2 Antibody (Phe26) - LS-C193128 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MED23 / SUR2 Antibody (Rhodamine) - LS-C183816 from LifeSpan Bioscience

Prices $800.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MED23 / SUR2 Antibody (aa531-630) - LS-C307096 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-MED23 / SUR2 Antibody (C-Terminus) - LS-C287319 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CRSP3 by Western Blot. Samples: Nuclear extract (5 and 25 ug) from HeLa cells. Antibody: Affinity purified rabbit anti-CRSP3 antibody used at 0.33 ug/ml. Detection: Chemiluminescence with an exposure time of 5 minutes.

Anti-MED23 / SUR2 Antibody (N-Terminus) - LS-C109980 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MED23 / DRIP130 antibody LS-C109980 Western blot of OVCAR-3 cell lysate.

Anti-MED23 / SUR2 Antibody (aa1-50) - LS-C287316 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CRSP3 by Immunoprecipitation. Samples: Nuclear extract (5 mg) from HeLa cells. Antibody: Affinity purified rabbit anti-CRSP3 antibody used at 4 ug/5 mg extract. Detection: Coomassie stain. The identity of the band that is CRSP3 was verified by mass spectrometry.

Anti-MED23 / SUR2 Antibody (aa1-50) - LS-C119322 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human colon carcinoma tissue, using MED23 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-MED23 / SUR2 Antibody (aa400-450) - LS-C287317 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human CRSP3 by Immunoprecipitation. Samples: Nuclear extract (5 mg) from HeLa cells. Antibody: Affinity purified rabbit anti-CRSP3 antibody used at 4 ug/5 mg extract. Detection: Coomassie stain. The identity of the band that is CRSP3 was verified by mass spectrometry.

Anti-MED23 / SUR2 Antibody (aa897-916) IHC-plus™ - LS-B3039 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-MED23 / DRIP130 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3039 dilution 1:100.

MED23 Antibody - NB200-338 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: MED23 Antibody [NB200-338] - Nuclear extract (5 mg) from HeLa cells. Antibody used at 4 ug/5 mg extract.

MED23 Antibody - NB200-337 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: MED23 Antibody [NB200-337] - Nuclear extract (5 mg) from HeLa cells. Antibody used at 4 ug/5 mg extract.

MED23 Antibody - NBP1-66374 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MED23 Antibody [NBP1-66374] - Analysis of A549 cells, using MED23 Antibody. The picture on the right is treated with the synthesized peptide.

MED23 Antibody - NB200-339 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MED23 Antibody [NB200-339] - Nuclear extract (5 and 25 ug) from HeLa cells. Antibody used at 0.33 ug/ml.

MED23 Antibody (4H6) - H00009439-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4H6
Sandwich ELISA: MED23 Antibody (4H6) [H00009439-M01] - Detection limit for recombinant GST tagged MED23 is 0.03 ng/ml as a capture antibody.

DRIP130/CRSP130 Polyclonal Antibody - bs-13032R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DRIP130/CRSP130 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13032R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DRIP130/CRSP130 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13032R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

DRIP130/CRSP130 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13032R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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