| Gene Symbol | MED23 |
|---|---|
| Entrez Gene | 9439 |
| Alt Symbol | ARC130, CRSP130, CRSP133, CRSP3, DRIP130, MRT18, SUR-2, SUR2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | mediator complex subunit 23 |
| Other Description | 130 kDa transcriptional co-activator|133 kDa transcriptional co-activator|activator-recruited cofactor 130 kDa component|cofactor required for Sp1 transcriptional activation subunit 3|mediator of RNA polymerase II transcription subunit 23|vitamin D3 receptor interacting protein |
| Swissprots | Q9NTU0 Q5JWT3 Q6P9H6 Q5JWT4 B9TX55 Q9NTT9 Q9Y667 Q9ULK4 Q9Y5P7 O95403 Q9H0J2 |
| Accessions | EAW48049 EAW48050 EAW48051 EAW48052 Q9ULK4 AB033042 BAA86530 AF104255 AAD12724 AF105332 AAD31729 AF135022 AAD30202 AI249380 AJ420587 AK304711 BAG65476 AK315030 AL136776 CAB66710 AM393572 CAL38449 AW295188 BC007088 AAH07088 BC060759 AAH60759 DB453121 EU392520 ACB88848 EU392521 ACB88849 EU392522 ACB88850 EU392523 ACB88851 EU392524 ACB88852 EU392525 ACB88853 EU392526 ACB88854 EU392527 ACB88855 EU392528 ACB88856 EU392529 ACB88857 EU392530 ACB88858 EU392531 ACB88859 EU392532 ACB88860 EU832308 ACE87565 EU832392 ACE86877 XM_005267223 XP_005267280 XM_006715612 XP_006715675 XM_011536257 XP_011534559 NM_001270521 NP_001257450 NM_001270522 NP_001257451 NM_004830 NP_004821 NM_015979 NP_057063 |
| Function | Required for transcriptional activation subsequent to the assembly of the preinitiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling. {ECO:0000250, ECO:0000269|PubMed:10353252, ECO:0000269|PubMed:14759369, ECO:0000269|PubMed:16595664}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
Mediator of RNA polymerase II transcription subunit 23 (MED23), Human, ELISA Kit - E01M0076 from ARP American Research Products
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7235843 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7235350 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7240735 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7211359 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7239306 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7218344 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7246772 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7205056 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7232987 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7247852 from MyBioSource
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Mediator of RNA polymerase II transcription subunit 23 (MED23), ELISA Kit - MBS7238910 from MyBioSource
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Human MED23 ELISA Kit - E089428 from Biobool
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