SPP1

Gene Symbol SPP1
Entrez Gene 6696
Alt Symbol BNSP, BSPI, ETA-1, OPN
Species Human
Gene Type protein-coding
Description secreted phosphoprotein 1
Other Description SPP1/CALPHA1 fusion|early T-lymphocyte activation 1|nephropontin|osteopontin|osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein|secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)|urinary stone protein|uropontin
Swissprots Q8NBK2 Q567T5 Q15683 B2RDA1 Q15682 Q4W597 Q15681 Q96IZ1 P10451
Accessions AAA86886 AAY41035 BAA03554 CAX69239 CBX54353 EAX06004 EAX06005 EAX06006 EAX06007 EAX06008 EAX06009 EAX06010 P10451 AA665210 AB209987 BAE45628 AB469789 BAH58215 AF052124 AAC28619 AK057738 AK075463 BAC11635 AK290090 BAF82779 AK290104 BAF82793 AK295491 BAH12087 AK296035 BAG58801 AK315461 BAG37848 AM392768 CAL37646 AM392898 CAL37776 AY956318 AAX59003 BC007016 AAH07016 BC017387 AAH17387 BC022844 AAH22844 BC093033 AAH93033 BF699765 BX648003 CB117856 D28759 BAA05949 D28760 BAA05950 D28761 BAA05951 DA419665 DQ839491 ABI63352 DQ846870 ABI63357 DQ846871 ABI63358 DQ892544 ABM83470 DQ895755 ABM86681 EU831940 ACE87381 EU832035 ACE86697 HQ874460 AEA49027 HQ874461 AEA49028 J04765 AAA59974 JF412666 AEA49030 JF412667 AEA49031 M83248 AAA17675 X13694 CAA31984 NM_000582 NP_000573 NM_001040058 NP_001035147 NM_001040060 NP_001035149 NM_001251829 NP_001238758 NM_001251830 NP_001238759
Function Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.
Subcellular Location Secreted.
Tissue Specificity Bone. Found in plasma.
Top Pathways Focal adhesion, ECM-receptor interaction, Toll-like receptor signaling pathway, PI3K-Akt signaling pathway

OPN CRISPR/Cas9 KO Plasmid (h) - sc-400219 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OPN HDR Plasmid (h) - sc-400219-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OPN Double Nickase Plasmid (h) - sc-400219-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OPN Double Nickase Plasmid (h2) - sc-400219-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OPN CRISPR Activation Plasmid (h) - sc-400219-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OPN CRISPR Activation Plasmid (h2) - sc-400219-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

OPN Lentiviral Activation Particles (h) - sc-400219-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OPN Lentiviral Activation Particles (h2) - sc-400219-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

OPN siRNA (h) - sc-36129 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OPN shRNA Plasmid (h) - sc-36129-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

OPN shRNA (h) Lentiviral Particles - sc-36129-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU077661 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1754 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1754 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05223 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05223

SPP1 siRNA (Human) - CRH4566 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPP1 - MBS8232750 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SPP1 (NM_000582.2) - SHH417112 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SPP1(NM_001040060.1) - SHL030030 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SPP1(NM_001040058.1) - SHL030160 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SPP1(NM_000582.2) - SHL030178 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SPP1(NM_001040060.1) - SHL030196 from Creative biogene

Category siRNA
Species Reactivities Human

Human Osteopontin siRNA - orb265068 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SPP1 shRNA Plasmid (Human) - CHH4566 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SPP1 miRNA 3'UTR clone - MiUTR1H-09862 from Creative biogene

Species Reactivities Human
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