Rel

Gene Symbol	Rel
Entrez Gene	19696
Alt Symbol	c-Rel
Species	Mouse
Gene Type	protein-coding
Description	reticuloendotheliosis oncogene
Other Description	C-Rel proto-oncogene protein\|proto-oncogene c-Rel
Swissprots	P15307
Accessions	EDL07897 P15307 AK031627 BC139447 AAI39448 BC139448 AAI39449 BC139770 AAI39771 X15842 CAA33843 X60271 CAA42817 NM_009044 NP_033070
Function	Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an in
Subcellular Location	Nucleus.
Top Pathways	Viral carcinogenesis, Transcriptional misregulation in cancer

Category	Protein
Source	Yeast or E.coli or Baculovirus or Mammalian cell
Species	Mouse

Category	Protein
Prices	$1,385.00, $1,385.00, $1,605.00, $1,605.00, $2,310.00, $2,310.00, $2,755.00, $2,755.00
Sizes	500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source	E Coli or Yeast or Baculovirus or Mammalian Cell
Species	Mouse

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