Gene Symbol | Rel |
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Entrez Gene | 19696 |
Alt Symbol | c-Rel |
Species | Mouse |
Gene Type | protein-coding |
Description | reticuloendotheliosis oncogene |
Other Description | C-Rel proto-oncogene protein|proto-oncogene c-Rel |
Swissprots | P15307 |
Accessions | EDL07897 P15307 AK031627 BC139447 AAI39448 BC139448 AAI39449 BC139770 AAI39771 X15842 CAA33843 X60271 CAA42817 NM_009044 NP_033070 |
Function | Proto-oncogene that may play a role in differentiation and lymphopoiesis. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an in |
Subcellular Location | Nucleus. |
Top Pathways | Viral carcinogenesis, Transcriptional misregulation in cancer |
c-Rel Antibody (290512) - MAB2699 from Novus Biologicals
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c-Rel Antibody (290512) [Biotin] - BAM2699 from Novus Biologicals
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Anti-REL antibody produced in rabbit - SAB2105282 from Sigma-Aldrich
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Rel antibody - middle region (ARP36966_P050) - ARP36966_P050 from Aviva Systems Biology
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REL Antibody - C-terminal region (ARP36967_P050) - ARP36967_P050 from Aviva Systems Biology
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cRel antibody - 10R-11006 from Fitzgerald
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Rel Antibody - GWB-MM508D from Genway Biotech
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Anti-Mouse c-Rel eFluor® 660 - 50-6111 from eBioscience
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Anti-Mouse c-Rel PE - 12-6111 from eBioscience
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Anti-Mouse c-Rel Purified - 14-6111 from eBioscience
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Polyclonal Antibody to V-Rel Reticuloendotheliosis Viral Oncogene Homolog (REL) - PAP741Mu01 from Cloud-clone
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Rel-Antibody-C-terminal-region-AI11080 - AI11080 from Abgent, a WuXi AppTec company
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cRel antibody - 70R-50314 from Fitzgerald
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Anti-c-Rel Picoband™ Antibody PB9741 - PB9741 from Boster Bio
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Anti-c-Rel Antibody - 10-P9741 from ARP American Research Products
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c-Rel Antibody (R31972) - R31972 from NSJ Bioreagent
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REL antibody - orb316604 from Biorbyt
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c-Rel, Polyclonal Antibody - MBS178033 from MyBioSource
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Rel antibody - middle region : Biotin (ARP36966_P050-Biotin) - ARP36966_P050-Biotin from Aviva Systems Biology
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Rel antibody - middle region : FITC (ARP36966_P050-FITC) - ARP36966_P050-FITC from Aviva Systems Biology
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Rel antibody - middle region : HRP (ARP36966_P050-HRP) - ARP36966_P050-HRP from Aviva Systems Biology
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Anti-REL Monoclonal antibody, clone 2SFMBI6 [PE] - CABT-BL8245 from Creative Diagnostics
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Anti-REL Monoclonal antibody, clone 2SFMBI6 - CABT-BL8246 from Creative Diagnostics
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Anti-c-Rel-Picoband-trade-Antibody - ABO12427 from Abgent, a WuXi AppTec company
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