PUS10

Gene Symbol PUS10
Entrez Gene 150962
Alt Symbol CCDC139, DOBI
Species Human
Gene Type protein-coding
Description pseudouridylate synthase 10
Other Description coiled-coil domain containing 139|coiled-coil domain-containing protein 139|pseudouridine synthase 10|psi55 synthase|putative tRNA pseudouridine synthase Pus10|tRNA pseudouridine 55 synthase|tRNA pseudouridylate synthase|tRNA-uridine isomerase
Swissprots Q3MIT2 Q5JPJ5 Q96MI8
Accessions EAX00022 EAX00023 EAX00024 EAX00025 EAX00026 EAX00027 Q3MIT2 AA878516 AK056874 BAB71300 AK291729 BAF84418 AL832208 CAI46123 BC065197 BC101680 AAI01681 BC101706 AAI01707 BC143480 BP354604 XM_006711952 XP_006712015 XM_011532568 XP_011530870 XM_011532569 XP_011530871 XM_011532570 XP_011530872 XM_011532571 XP_011530873 XM_011532572 XP_011530874 XM_011532573 XP_011530875 XM_011532574 XP_011530876 XM_011532575 XP_011530877 XM_011532576 XP_011530878 XM_011532577 XP_011530879 XM_011532578 XP_011530880 NM_144709 NP_653310
Function Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death. {ECO:0000269|PubMed:14527409, ECO:0000269|PubMed:19712588, ECO:0000305}.

PUS10 (E-19) - sc-242345 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PUS10 (K-17) - sc-242347 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PUS10 (S-16) - sc-242346 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PUS10 antibody - ab185078 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PUS10 antibody (ab185078) at 1/500 dilution + RT4 cell lysate

Anti-PUS10 antibody - ab184981 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human nasopharynx tissue, labeling PUS10 with ab184981 at 1/50 dilution.

Anti-PUS10 antibody - ab103797 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 antibody - N-terminal - ab156124 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PUS10 antibody - N-terminal (ab156124) at 1/100 dilution + A549 cell line lysate at 35 µg

Anti-PUS10 Antibody (aa52-78, APC) - LS-C223796 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 Antibody (aa52-78, AP) - LS-C223797 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 Antibody (aa52-78, Biotin) - LS-C223798 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 Antibody (aa52-78, FITC) - LS-C223799 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 Antibody (aa52-78, Azide-free, HRP) - LS-C223800 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 Antibody (aa52-78, PE) - LS-C223801 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 Antibody (aa52-78) - LS-C324431 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 Antibody (aa287-336) - LS-C111424 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PUS10 antibody LS-C111424 Western blot of HCT15 cell lysate.

Anti-PUS10 Antibody (aa52-78) - LS-C155893 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PUS10 Antibody western blot of A549 cell line lysates (35 ug/lane). The PUS10 antibody detected the PUS10 protein (arrow).

PUS10 Antibody - NBP1-56369 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PUS10 Antibody [NBP1-56369] - HCT15 cell lysate, concentration 0.2-1 ug/ml.

PUS10 Antibody - NBP2-30613 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PUS10 Antibody [NBP2-30613] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10Lane 2: Negative control (vector only transfected HEK293T lysate)Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY408160)

CCDC139 Polyclonal Antibody - bs-7102R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PUS10 antibody produced in rabbit - HPA049582 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PUS10: <B>Cat. No. HPA049582</B>: Immunohistochemical staining of human cerebral cortex shows moderate nuclear positivity in neuronal cells.

Anti-PUS10 (466-480) antibody produced in rabbit - SAB1104492 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human PUS10 was separated on SDS-PAGE, blotted with Anti-PUS10 (466-480) (<B>Cat. No. SAB1104492</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-PUS10 antibody produced in rabbit - SAB2105871 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PUS10: <B>Cat. No. SAB2105871</B>: CCDC139 in HCT15 cell lysates with CCDC139 antibody at 1.0 μg/mL.

Anti-PUS10 (291-304) antibody produced in rabbit - SAB1104491 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human PUS10 was separated on SDS-PAGE, blotted with Anti-PUS10 (291-304) (<B>Cat. No. SAB1104491</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:500

Anti-PUS10 antibody produced in rabbit - HPA044736 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PUS10: <B>Cat. No. HPA044736</B>: Immunohistochemical staining of human nasopharynx shows moderate nuclear and cytoplasmic positivity in respiratory epithelial cells.

PUS10 antibody - middle region (ARP52750_P050) - ARP52750_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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