KCNN4

Gene Symbol	KCNN4
Entrez Gene	3783
Alt Symbol	IK, IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4
Species	Human
Gene Type	protein-coding
Description	potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
Other Description	SKCa 4|SKCa4|intermediate conductance calcium-activated potassium channel protein 4|potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4|putative Gardos channel|putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel|small conductance calcium-activated potassium channel 4
Swissprots	Q53XR4 O15554
Accessions	AAG26917 CAB70490 CBM42811 EAW57229 EAW57230 O15554 AB128983 BAI52725 AB128984 BAI52726 AB128985 BAI52727 AF000972 AAB82739 AF022150 AAC23541 AF022797 AAC51913 AF033021 AAC36804 AF053403 AAC35281 AF395661 AAK81862 BC015337 AAH15337 BT007426 AAP36094 DQ891493 ABM82419 DQ894684 ABM85610 XM_005258882 XP_005258939 XM_005258883 XP_005258940 XM_011526938 XP_011525240 XR_935823 NM_002250 NP_002241
Function	Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin. {ECO:0000269|PubMed:17157250, ECO:0000269|PubMed:18796614}.
Subcellular Location	Membrane; Multi-pass membrane protein.
Tissue Specificity	Widely expressed in non-excitable tissues.
Top Pathways	Salivary secretion, Protein digestion and absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KCNN4 peptide - ab87266 from Abcam Category Peptide

Human KCNN4 protein fragment - ab158789 from Abcam Category Protein Source Wheat germ Species Human

KCNN4 / KCa3.1 Antibody Blocking Peptide - LS-E29694 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KCNN4 / KCa3.1 Antibody Blocking Peptide - LS-E29696 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human KCNN4 Protein - H00003783-Q01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

KCNN4 Blocking Peptide - 33R-2063 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

KCNN4 - H00003783-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

KCNN4 fusion protein - ag19778 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

KCNN4 fusion protein - ag19774 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

IKCA1 (KCNN4) - HEK293 Recombinant Cell line - GWB-PS037F from Genway Biotech Category Protein Prices $31,000.00 Sizes 2x10cells (6) Species Human

KCNN4 Recombinant Protein Antigen - NBP2-33694PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

KCNN4 Protein - NBP2-32484PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

KCNN4 Peptide, Human - M34GP07998H from Creative Peptides Category Peptide Source Synthetic. Species Human

KCNN4 fusion protein - Ag22545 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

KCNN4 fusion protein - Ag22551 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

Intermediate conductance calcium-activated potassium channel protein 4 (KCNN4), Recombinant Protein - MBS7017767 from MyBioSource Category Protein Prices $1,230.00, $2,215.00, $3,425.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Intermediate conductance calcium-activated potassium channel protein 4 (KCNN4), Recombinant Protein - MBS1024758 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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