Txnrd2

Gene Symbol Txnrd2
Entrez Gene 26462
Alt Symbol AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd2
Species Mouse
Gene Type protein-coding
Description thioredoxin reductase 2
Other Description TR beta|thioredoxin reductase 2, mitochondrial|thioredoxin reductase TR3
Swissprots Q91YX4 Q9JMH5 Q9JHA7 Q80VZ4 Q6KG49 Q9JLT4
Accessions AAL90457 EDK97524 EDK97525 EDK97526 Q9JLT4 AB027566 BAA86986 AF136399 AAF03359 AF171053 AAD51323 AF412308 AAQ03230 AK008004 BAB25403 AK075828 AK181417 AK186982 AK188250 BC013688 AAH13688 BC029344 BC052157 AAH52157 BC052758 BF465261 NM_013711 NP_038739
Function Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.
Subcellular Location Mitochondrion {ECO:0000269|PubMed:10721726}.
Tissue Specificity Expressed in liver, heart, testis and kidney. {ECO:0000269|PubMed:10455115, ECO:0000269|PubMed:10500251, ECO:0000269|PubMed:10721726}.
Top Pathways Selenocompound metabolism, Pyrimidine metabolism

TrxR2 (F-5) - sc-376868 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TrxR2 (F-5): sc-376868. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing cytoplasmic localization.

TrxR2 (M-50) - sc-67127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TrxR2 (M-50): sc-67127. Western blot analysis of TrxR2 expression in non-transfected: sc-117752 (A) and mouse TrxR2 transfected: sc-124315 (B) 293T whole cell lysates.

TR beta antibody (Ser142) - 70R-34598 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

TR beta antibody (Ser142) - 70R-34599 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Thioredoxin Reductase 2 Antibody, clone 1C4 - MABS179 from EMD Millipore

Prices $269.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 1C4

Thioredoxin reductase 2 / TXNRD2 antibody - AM50583PU-N from Acris Antibodies

Prices $330.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 1C4
Western Blotting Analysis: Representative lot data. NIH3T3 cell lysate was probed with Anti-Thioredoxin Reductase 2, clone 1C4 (0.5 µg/mL). Proteins were visualized using a Goat Anti-Rat IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates Thioredoxin 2 (~57 kDa).

Anti-Thioredoxin Reductase 2 Antibody, clone 1C4 - MABS179 from Sigma-Aldrich

Prices $269.00
Sizes mabs179
Clonality Monoclonal
Western Blotting Analysis: <br /> Representative lot data. <br /> NIH3T3 cell lysate was probed with Anti-Thioredoxin Reductase 2, clone 1C4 (0.5 µg/mL). <br /> Proteins were visualized using a Goat Anti-Rat IgG secondary antibody conjugated to HRP and a chemiluminescence detection system. <br /> Arrow indicates Thioredoxin 2 (~57 kDa).

Mouse Thioredoxin Reductase 1/2 (mTR1/2) Polyclonal Antibody - bs-50594R from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1 : L929 Cell Lysate; Lane 2 : NIH3T3 Cell Lysate; Lane 3 : Mouse Liver Tissue; Lane 4 : Rat Liver Tissue; probed with Mouse Thioredoxin Reductase 1/2 (mTR1/2) Polyclonal Antibody, unconjugated (bs-50594R) at 1:5000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at Room Temperature.

mTr2 Polyclonal Antibody - bs-50605R from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Lane 1 : L929 Cell Lysate; Lane 2 : NIH3T3 Cell Lysate; Lane 3 : Mouse Liver Tissue; Lane 4 : Mouse Brain Tissue; probed with mTr2 Polyclonal Antibody, unconjugated (bs-50605R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at Room Temperature.
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