| Gene Symbol |
Txnrd2
|
| Entrez Gene |
26462
|
| Alt Symbol |
AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd2
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
thioredoxin reductase 2
|
| Other Description |
TR beta|thioredoxin reductase 2, mitochondrial|thioredoxin reductase TR3
|
| Swissprots |
Q91YX4 Q9JMH5 Q9JHA7 Q80VZ4 Q6KG49 Q9JLT4
|
| Accessions |
AAL90457 EDK97524 EDK97525 EDK97526 Q9JLT4 AB027566 BAA86986 AF136399 AAF03359 AF171053 AAD51323 AF412308 AAQ03230 AK008004 BAB25403 AK075828 AK181417 AK186982 AK188250 BC013688 AAH13688 BC029344 BC052157 AAH52157 BC052758 BF465261 NM_013711 NP_038739
|
| Function |
Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:10721726}.
|
| Tissue Specificity |
Expressed in liver, heart, testis and kidney. {ECO:0000269|PubMed:10455115, ECO:0000269|PubMed:10500251, ECO:0000269|PubMed:10721726}.
|
| Top Pathways |
Selenocompound metabolism, Pyrimidine metabolism
|