| Gene Symbol | Txnrd2 |
|---|---|
| Entrez Gene | 26462 |
| Alt Symbol | AA118373, ESTM573010, TGR, Tr3, Trxr2, Trxrd2 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | thioredoxin reductase 2 |
| Other Description | TR beta|thioredoxin reductase 2, mitochondrial|thioredoxin reductase TR3 |
| Swissprots | Q91YX4 Q9JMH5 Q9JHA7 Q80VZ4 Q6KG49 Q9JLT4 |
| Accessions | AAL90457 EDK97524 EDK97525 EDK97526 Q9JLT4 AB027566 BAA86986 AF136399 AAF03359 AF171053 AAD51323 AF412308 AAQ03230 AK008004 BAB25403 AK075828 AK181417 AK186982 AK188250 BC013688 AAH13688 BC029344 BC052157 AAH52157 BC052758 BF465261 NM_013711 NP_038739 |
| Function | Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox- regulated cell signaling. |
| Subcellular Location | Mitochondrion {ECO:0000269|PubMed:10721726}. |
| Tissue Specificity | Expressed in liver, heart, testis and kidney. {ECO:0000269|PubMed:10455115, ECO:0000269|PubMed:10500251, ECO:0000269|PubMed:10721726}. |
| Top Pathways | Selenocompound metabolism, Pyrimidine metabolism |