| Gene Symbol |
CFAP126
|
| Entrez Gene |
257177
|
| Alt Symbol |
C1orf192, Flattop, Fltp
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cilia and flagella associated protein 126
|
| Other Description |
UPF0740 protein C1orf192|cilia- and flagella-associated protein 126|protein Flattop
|
| Swissprots |
Q5VTH2
|
| Accessions |
EAW52596 Q5VTH2 BU688150 DT215043 NM_001013625 NP_001013647
|
| Function |
Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. {ECO:0000250|UniProtKB:Q6P8X9}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q6P8X9}. Cell projection, cilium {ECO:0000250|UniProtKB:Q6P8X9}. Apical cell membrane {ECO:0000250|UniProtKB:Q6P8X9}. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells. {ECO:0000250|UniProtKB:Q6P8X9}.
|