| Gene Symbol |
CFAP126
|
| Entrez Gene |
257177
|
| Alt Symbol |
C1orf192, Flattop, Fltp
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cilia and flagella associated protein 126
|
| Other Description |
UPF0740 protein C1orf192|cilia- and flagella-associated protein 126|protein Flattop
|
| Swissprots |
Q5VTH2
|
| Accessions |
EAW52596 Q5VTH2 BU688150 DT215043 NM_001013625 NP_001013647
|
| Function |
Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. {ECO:0000250|UniProtKB:Q6P8X9}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q6P8X9}. Cell projection, cilium {ECO:0000250|UniProtKB:Q6P8X9}. Apical cell membrane {ECO:0000250|UniProtKB:Q6P8X9}. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells. {ECO:0000250|UniProtKB:Q6P8X9}.
|
![Western Blot: C1orf192 Overexpression Lysate (Adult Normal) [NBP2-08723] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C1orf192.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3202_C1orf192%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08723-img0001.jpg)