Gene Symbol | CFAP126 |
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Entrez Gene | 257177 |
Alt Symbol | C1orf192, Flattop, Fltp |
Species | Human |
Gene Type | protein-coding |
Description | cilia and flagella associated protein 126 |
Other Description | UPF0740 protein C1orf192|cilia- and flagella-associated protein 126|protein Flattop |
Swissprots | Q5VTH2 |
Accessions | EAW52596 Q5VTH2 BU688150 DT215043 NM_001013625 NP_001013647 |
Function | Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells. Regulates basal body docking and cilia formation in multiciliated lung cells. Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear. {ECO:0000250|UniProtKB:Q6P8X9}. |
Subcellular Location | Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q6P8X9}. Cell projection, cilium {ECO:0000250|UniProtKB:Q6P8X9}. Apical cell membrane {ECO:0000250|UniProtKB:Q6P8X9}. Note=Localizes to the apical cell membrane, the basal body and the primary cilium in monociliated node cells. {ECO:0000250|UniProtKB:Q6P8X9}. |
C1orf192 CRISPR/Cas9 KO Plasmid (h) - sc-407237 from Santa Cruz Biotechnology
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C1orf192 HDR Plasmid (h) - sc-407237-HDR from Santa Cruz Biotechnology
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C1orf192 Double Nickase Plasmid (h) - sc-407237-NIC from Santa Cruz Biotechnology
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C1orf192 Double Nickase Plasmid (h2) - sc-407237-NIC-2 from Santa Cruz Biotechnology
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C1orf192 CRISPR Activation Plasmid (h) - sc-407237-ACT from Santa Cruz Biotechnology
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C1orf192 CRISPR Activation Plasmid (h2) - sc-407237-ACT-2 from Santa Cruz Biotechnology
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C1orf192 Lentiviral Activation Particles (h) - sc-407237-LAC from Santa Cruz Biotechnology
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C1orf192 Lentiviral Activation Particles (h2) - sc-407237-LAC-2 from Santa Cruz Biotechnology
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C1orf192 siRNA (h) - sc-88671 from Santa Cruz Biotechnology
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C1orf192 shRNA Plasmid (h) - sc-88671-SH from Santa Cruz Biotechnology
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C1orf192 shRNA (h) Lentiviral Particles - sc-88671-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU132361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4625 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4625 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01112 from Sigma-Aldrich
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C1orf192 siRNA (Human) - CRJ6784 from Cohesion Biosciences
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C1orf192 - MBS829154 from MyBioSource
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shRNA set against Human C1orf192 (NM_001013625.2) - SHH250490 from Creative biogene
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C1orf192 shRNA Plasmid (Human) - CHJ6784 from Cohesion Biosciences
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C1ORF192 miRNA 3'UTR clone - MiUTR1H-01248 from Creative biogene
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