U2AF1

Gene Symbol U2AF1
Entrez Gene 7307
Alt Symbol FP793, RN, RNU2AF1, U2AF35, U2AFBP
Species Human
Gene Type protein-coding
Description U2 small nuclear RNA auxiliary factor 1
Other Description U2 small nuclear RNA auxillary factor 1|U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit|U2 snRNP auxiliary factor small subunit|U2(RNU2) small nuclear RNA auxiliary factor binding protein|splicing factor U2AF 35 kDa subunit|splicing factor U2AF 35kDa subunit
Swissprots Q01081 Q71RF1 Q701P4
Accessions BAA95534 EAX09501 EAX09502 EAX09503 EAX09504 EAX09505 EAX09506 Q01081 AB451244 BAG70058 AF370386 AAQ15222 AJ627978 CAF29556 AK022152 AK023589 AK094435 AK098266 AK307560 AL832665 CAH10401 BC001177 AAH01177 BC001923 AAH01923 BC005915 AAH05915 BC013786 BC032521 CB110007 HQ447764 ADQ32249 M96982 AAA36619 XM_011529743 XP_011528045 NM_001025203 NP_001020374 NM_001025204 NP_001020375 NM_006758 NP_006749
Function Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. {ECO:0000269|PubMed:8647433}.
Subcellular Location Nucleus {ECO:0000269|PubMed:15096518}. Nucleus speckle {ECO:0000269|PubMed:15096518}.
Top Pathways Spliceosome

Human U2AF35 full length protein - ab152778 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab152778 stained with Coomassie Blue.

Human U2AF35 full length protein - ab156324 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of ab156324 (3µg).

U2AF1 Antibody Blocking Peptide - LS-E14692 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

U2AF1 Antibody Blocking Peptide - LS-E7110 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

U2AF1 Antibody Blocking Peptide - LS-E7111 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human U2AF35 Protein - H00007307-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

U2AF35 Partial Recombinant Protein - H00007307-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

U2AF1-Antibody-Center-Y114-Blocking-Peptide - BP2802d from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

U2AF1-Antibody-Center-S70-Blocking-Peptide - BP2802c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human U2AF1 protein - orb191367 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Source E. coli
Species Human

U2AF1 Blocking Peptide - 33R-5649 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

U2AF1 protein (His tag) - 80R-2800 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

U2AF1 / U2AF35 (1-240, His-tag) - AR50919PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
U2AF1 / U2AF35

U2AF1 / U2AF35 (1-240, His-tag) - AR50919PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
U2AF1 / U2AF35

U2AF1 / U2AF35 - H00007307-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

U2AF1 / U2AF35 - H00007307-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

U2AF1 / U2AF35 - H00007307-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

U2AF1, 1-240aa, Human, His tag, E.coli - 01-P2095 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

U2AF35 fusion protein - ag0399 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human U2 small nuclear RNA auxiliary factor 1, His-tagged - U2AF1-580H from Creative Biomart

Category Protein
Source E.coli
Species Human

u2AF1, 1-240aa, Human, His tag, E.coli (Denatured) - ATGP2095 from ATGen

Category Protein
Prices $80.00, $240.00, $720.00
Sizes 20 µg, 100 µg, 500 µg
Species Human
SDSPAGE

U2AF35 Protein - NBP1-92553PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

U2AF1 Peptide, Human - M34GP16922H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

u2AF1 - PAT-82094-1 from Nordic BioSite

Category Protein
Species Human
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