LRP2

Gene Symbol LRP2
Entrez Gene 4036
Alt Symbol DBS, GP330
Species Human
Gene Type protein-coding
Description low density lipoprotein receptor-related protein 2
Other Description Heymann nephritis antigen homolog|LRP-2|calcium sensor protein|glycoprotein 330|low-density lipoprotein receptor-related protein 2|megalin
Swissprots O00711 Q16215 P98164
Accessions AAC17129 AAX88965 AAY24266 CCQ43266 EAX11280 P98164 AK295005 BAG58066 AK302843 BAG64033 AY265357 AAP88585 AY265358 AAP88586 CD673312 DA200673 DA339827 DA401915 S73145 AAB30825 U04441 AAB02882 U33837 AAB41649 XM_011511183 XP_011509485 XM_011511184 XP_011509486 XM_011511185 XP_011509487 NM_004525 NP_004516
Function Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid- hormone and para-thyroid-hormone-related protein release. {ECO:0000250}.
Subcellular Location Membrane; Single-pass type I membrane protein. Membrane, coated pit.
Tissue Specificity Absorptive epithelia, including renal proximal tubules.
Top Pathways Hedgehog signaling pathway, Thyroid hormone synthesis

megalin (C-19) - sc-16476 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

megalin (H-245) - sc-25470 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
megalin (H-245): sc-25470. Western blot analysis of human recombinant megalin.

Anti-Lrp2 / Megalin antibody - ab76969 from Abcam

Prices $387.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
IHC image of ab76969 staining in human kidney carcinoma formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab76969, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Anti-Lrp2 / Megalin antibody - ab101011 from Abcam

Prices $372.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Lrp2 / Megalin antibody - ab115316 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115316 at 2.5ug/ml staining Lrp2/Megalin in Human kidney cortex tissue by immunohistochemistry. Following primary incubation the slides were incubated with biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Lrp2 / Megalin antibody - ab56014 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Lrp2 / Megalin antibody [CD7D5] - ab184676 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone CD7D5
Immunohistochemical analysis of formalin-fixed, paraffin-embedded mouse kidney tissue labeling Lrp2 / Megalin with ab184676 at 1/100 dilution.

Anti-Lrp2 / Megalin antibody [EPR5875] - ab129198 from Abcam

Host Rabbit
Clonality Monoclonal
Clone EPR5875
All lanes : Anti-Lrp2 / Megalin antibody [EPR5875] (ab129198) at 1/1000 dilutionLane 1 : Human thyroid lysateLane 2 : 293T lysateLane 3 : Human adrenal gland lysateLane 4 : Caco 2 lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-LRP2 / Megalin Antibody (aa4641-4655) IHC-plus™ - LS-B105 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Megalin antibody IHC of human kidney cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B105 concentration 5 ug/ml.

Anti-LRP2 / Megalin Antibody (clone CD7D5) - LS-C194826 from LifeSpan Bioscience

Prices $740.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CD7D5

Anti-LRP2 / Megalin Antibody (C-Terminus) - LS-C145128 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LRP2 / Megalin Antibody (C-Terminus, AP) - LS-C278933 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRP2 / Megalin Antibody (C-Terminus, APC) - LS-C278935 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRP2 / Megalin Antibody (C-Terminus, Biotin) - LS-C278936 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRP2 / Megalin Antibody (C-Terminus, FITC) - LS-C278937 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRP2 / Megalin Antibody (C-Terminus, Azide-free, HRP) - LS-C278938 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRP2 / Megalin Antibody (C-Terminus, PE) - LS-C278939 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRP2 / Megalin Antibody (C-Terminus) - LS-C330507 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-LRP2 / Megalin Antibody (Cytoplasmic Domain, clone EPR5875) - LS-C154461 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone EPR5875
Western blot analysis on (A) human thyroid, (B) 293T, (C) human adrenal gland, and (D) Caco-2 lysates using anti-Megalin antibody.

Anti-LRP2 / Megalin Antibody (N-Terminus) - LS-C47074 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

LRP2 Antibody (CD7D5) - NB110-96417 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone CD7D5
Immunocytochemistry/Immunofluorescence: LRP2 Antibody (CD7D5) [NB110-96417] - Immunofluorescence staining of Megalin in the brush border of the proximal tubule.

LRP2 Antibody - NBP2-39033 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: LRP2 Antibody [NBP2-39033] - Immunofluorescent staining of human cell line HEK 293 shows positivity in mitochondria.

LRP2 Antibody - NBP1-85292 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: LRP2 Antibody [NBP1-85292] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10. Lane 2: Human Esophagus tissue.

LRP2 Antibody - NBP1-02540 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-LRP2 antibody produced in rabbit - SAB4301021 from Sigma-Aldrich

Prices $230.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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