| Gene Symbol |
LRP2
|
| Entrez Gene |
4036
|
| Alt Symbol |
DBS, GP330
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
low density lipoprotein receptor-related protein 2
|
| Other Description |
Heymann nephritis antigen homolog|LRP-2|calcium sensor protein|glycoprotein 330|low-density lipoprotein receptor-related protein 2|megalin
|
| Swissprots |
O00711 Q16215 P98164
|
| Accessions |
AAC17129 AAX88965 AAY24266 CCQ43266 EAX11280 P98164 AK295005 BAG58066 AK302843 BAG64033 AY265357 AAP88585 AY265358 AAP88586 CD673312 DA200673 DA339827 DA401915 S73145 AAB30825 U04441 AAB02882 U33837 AAB41649 XM_011511183 XP_011509485 XM_011511184 XP_011509486 XM_011511185 XP_011509487 NM_004525 NP_004516
|
| Function |
Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid- hormone and para-thyroid-hormone-related protein release. {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein. Membrane, coated pit.
|
| Tissue Specificity |
Absorptive epithelia, including renal proximal tubules.
|
| Top Pathways |
Hedgehog signaling pathway, Thyroid hormone synthesis
|