TIPIN

Gene Symbol TIPIN
Entrez Gene 54962
Alt Symbol -
Species Human
Gene Type protein-coding
Description TIMELESS interacting protein
Other Description CSM3 homolog|TIMELESS-interacting protein
Swissprots Q9NWZ6 Q9BVW5 B2CW64
Accessions ACB21044 EAW77762 EAW77763 Q9BVW5 AK000523 BAA91229 AK299233 BAG61265 BC000870 AAH00870 BK001386 DAA01365 BU596053 BU688750 XM_005254521 XP_005254578 XM_005254522 XP_005254579 XM_006720594 XP_006720657 XM_011521743 XP_011520045 NM_001289986 NP_001276915 NM_017858 NP_060328
Function Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress. {ECO:0000269|PubMed:17102137, ECO:0000269|PubMed:17116885, ECO:0000269|PubMed:17296725}.
Subcellular Location Cytoplasm. Nucleus.

TIPIN (C-13) - sc-160864 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TIPIN (C-13): sc-160864. Western blot analysis of TIPIN expression in SHP-77 whole cell lysate.

TIPIN (4C9) - sc-135580 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
TIPIN (4C9): sc-135580. Western blot analysis of TIPIN expression in human TIPIN transfected (A) and non-transfected (B) 293T whole cell lysates.

TIPIN (Z-25) - sc-134090 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
TIPIN (Z-25): sc-134090. Western blot analysis of TIPIN expression in Jurkat whole cell lysate.

Anti-TIPIN antibody - ab57488 from Abcam

Prices $380.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
ab57488 (1/200) detecting TIPIN in assynchronous HeLa cells (green). Cells were fixed in Paraformadehyde, permeabilised in 0.5% Triton X100/PBS and counterstained with DAPI in order to highlight the nucleus (red). Please refer to abreview for further experimental details.See Abreview

Anti-TIPIN antibody - ab75318 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN antibody - ab102792 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TIPIN antibody (ab102792) at 1/500 dilution + Human Kidney Lysate at 50 µg

Anti-TIPIN antibody - ab172792 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-TIPIN antibody (ab172792) at 1 µg/mlLane 1 : TIPIN transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-TIPIN antibody - ab80471 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-TIPIN antibody - N-terminal - ab156122 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TIPIN antibody - N-terminal (ab156122) at 1/100 dilution + Hela cell line lysate at 35 µg

Anti-TIPIN Antibody (N-Terminus) - LS-C144893 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa227-254, AP) - LS-C271536 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa227-254, APC) - LS-C271537 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa227-254, Biotin) - LS-C271538 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa227-254, FITC) - LS-C271539 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa227-254, Azide-free, HRP) - LS-C271540 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa227-254, PE) - LS-C271541 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa182-231) - LS-C81585 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-TIPIN Antibody (aa125-175) - LS-C288268 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (N-Terminus) - LS-C81584 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.

Anti-TIPIN Antibody (aa251-301) - LS-C288269 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa227-254) - LS-C325735 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TIPIN Antibody (aa227-254) - LS-C156224 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TIPIN Antibody western blot of HeLa cell line lysates (35 ug/lane). The TIPIN antibody detected the TIPIN protein (arrow).

Anti-TIPIN Antibody (clone 2E2) - LS-C336746 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIPIN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIPIN.

Anti-TIPIN Antibody (clone 3B11) - LS-C336760 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3B11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIPIN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIPIN.

Anti-TIPIN Antibody (clone 1A3) - LS-C336762 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A3
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIPIN (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIPIN.
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