IL27RA

Gene Symbol IL27RA
Entrez Gene 9466
Alt Symbol CRL1, IL-27RA, IL27R, TCCR, WSX1, zcytor1
Species Human
Gene Type protein-coding
Description interleukin 27 receptor, alpha
Other Description IL-27 receptor subunit alpha|IL-27R subunit alpha|IL-27R-alpha|T-cell cytokine receptor type 1|class I cytokine receptor|cytokine receptor WSX-1|cytokine receptor-like 1|interleukin-27 receptor subunit alpha|type I T-cell cytokine receptor
Swissprots A0N0L1 Q6UWB1 O60624
Accessions ABK41902 CAV32862 CBX32720 EAW84389 EAW84390 Q6UWB1 AF053004 AAC39755 AF106912 AAG26090 AF265242 AAG27297 AI983115 AW298502 AY358876 AAQ89235 BC028003 AAH28003 DQ891051 ABM81977 DQ894230 ABM85156 NM_004843 NP_004834
Function Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1- type immune responses. Also appears to be involved in innate defense mechanisms. {ECO:0000269|PubMed:14764690}.
Subcellular Location Membrane; Single-pass type I membrane protein.
Tissue Specificity Highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed in other tissues examined including heart, brain, fetal and adult lung, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine, kidney and colon. In the lymphoid system, higher level expression in CD4+ T-cell subsets than in CD8+ T-cell subsets. Also weaker expression in CD19+ B- cells and monocytes. {ECO:0000269|PubMed:11057672, ECO:0000269|PubMed:9600072}.

IL-27Rα (F-7) - sc-376309 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-27Rα (F-7): sc-376309. Western blot analysis of IL-27Rα expression in non-transfected: sc-117752 (A) and human IL-27Rα transfected: sc-114657 (B) 293T whole cell lysates.

IL-27Rα (H-250) - sc-99083 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IL-27Rα (H-250): sc-99083. Western blot analysis of IL-27Rα expression in human spleen tissue extract.

IL-27Rα (C-15) - sc-47066 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

IL-27Rα (J126) - sc-80078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
IL-27Rα (J126): sc-80078. Western blot analysis of IL-27Rα expression in non-transfected: sc-117752 (A) and human IL-27Rα transfected: sc-114657 (B) 293T whole cell lysates.

Anti-TCCR antibody - ab5996 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-TCCR antibody (ab5996) at 1 µg/ml + Human spleen tissue lysate

Anti-TCCR antibody - ab5997 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of TCCR expression in human spleen tissue lysates with ab5997 at 1 µg /ml.

Anti-TCCR antibody - ab197151 from Abcam

Prices $370.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
Anti-TCCR antibody (ab197151) at 1/500 dilution + Human fetal spleen lysate

Anti-TCCR antibody [IMG34N4G11] - ab139196 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone IMG34N4G11
Flow cytometic analysis of Human peripheral blood labelling TCCR with ab139196 at 1 µg/106 cells (red represents specific antibody and green represents isotype control).

Anti-TCCR antibody [MM0563-8A5] - ab89745 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0563-8A5

Anti-IL27RA Antibody (aa569-602) - LS-C344620 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from T47D cell line with IL27RA Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35 ug.

Anti-IL27RA Antibody (aa44-59) IHC-plus™ - LS-B574 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-IL27RA antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B574 concentration 5 ug/ml.

Anti-IL27RA Antibody (aa611-625) IHC-plus™ - LS-B1367 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-IL27RA antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1367 concentration 5 ug/ml.

Anti-IL27RA / WSX-1 Antibody (N-Terminus) - LS-C89426 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-IL27RA / WSX-1 Antibody (aa326-339) - LS-C148062 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-IL27RA Antibody - LS-C153085 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL27RA / WSX-1 Antibody (aa166-181) - LS-C148061 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-IL27RA Antibody (C-Terminus) - LS-C90049 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL27RA Antibody - LS-C153086 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL27RA Antibody (Extracellular Domain, CF) - LS-C130290 from LifeSpan Bioscience

Prices $445.00
Sizes 100 tst
Host Rat
Clonality Monoclonal

Anti-IL27RA Antibody (clone 11n183, PE) - LS-C184901 from LifeSpan Bioscience

Prices $530.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 11n183

Anti-IL27RA Antibody (clone 11n184, PE) - LS-C184902 from LifeSpan Bioscience

Prices $530.00
Sizes 100 tst
Host Rat
Clonality Monoclonal
Clone 11n184

Anti-IL27RA Antibody (aa123-343, Biotin) - LS-C298740 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL27RA Antibody (aa123-343, FITC) - LS-C302380 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL27RA Antibody (aa117-350, Biotin) - LS-C298794 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-IL27RA Antibody (aa117-350, FITC) - LS-C302965 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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