IL27RA

Gene Symbol	IL27RA
Entrez Gene	9466
Alt Symbol	CRL1, IL-27RA, IL27R, TCCR, WSX1, zcytor1
Species	Human
Gene Type	protein-coding
Description	interleukin 27 receptor, alpha
Other Description	IL-27 receptor subunit alpha|IL-27R subunit alpha|IL-27R-alpha|T-cell cytokine receptor type 1|class I cytokine receptor|cytokine receptor WSX-1|cytokine receptor-like 1|interleukin-27 receptor subunit alpha|type I T-cell cytokine receptor
Swissprots	A0N0L1 Q6UWB1 O60624
Accessions	ABK41902 CAV32862 CBX32720 EAW84389 EAW84390 Q6UWB1 AF053004 AAC39755 AF106912 AAG26090 AF265242 AAG27297 AI983115 AW298502 AY358876 AAQ89235 BC028003 AAH28003 DQ891051 ABM81977 DQ894230 ABM85156 NM_004843 NP_004834
Function	Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1- type immune responses. Also appears to be involved in innate defense mechanisms. {ECO:0000269|PubMed:14764690}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed in other tissues examined including heart, brain, fetal and adult lung, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine, kidney and colon. In the lymphoid system, higher level expression in CD4+ T-cell subsets than in CD8+ T-cell subsets. Also weaker expression in CD19+ B- cells and monocytes. {ECO:0000269|PubMed:11057672, ECO:0000269|PubMed:9600072}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human TCCR protein fragment - ab191679 from Abcam Category Protein Prices $515.00 Sizes 100 µg Source HEK 293 cells Species Human

Human TCCR peptide - ab39872 from Abcam Category Peptide Species Human

Human TCCR peptide - ab39858 from Abcam Category Peptide Species Human

Human TCCR protein fragment - ab127071 from Abcam Category Protein Source E. coli Species Human

IL27RA Antibody Blocking Peptide - LS-E29972 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

IL27RA Antibody Blocking Peptide - LS-E29973 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human IL-27 R alpha/WSX-1/TCCR Protein - H00009466-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

IL-27 R alpha/WSX-1/TCCR Peptide - NBP1-76727PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

IL-27 R alpha/WSX-1/TCCR Blocking Peptide - NBP1-76728PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human IL-27 Ra/WSX-1/TCCR Fc Chimera, CF - 1479-TC-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human IL27Ra Protein - abx067516 from Abbexa Category Protein Source E.coli Species Human

IL-27RA Blocking Peptide - abx063589 from Abbexa Category Peptide Species Human, Mouse, Rat

TCCR / IL27RA - H00009466-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TCCR / IL27RA - H00009466-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TCCR / IL27RA Control Peptide - AP30861CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

TCCR / IL27RA Control Peptide - AP30862CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

TCCR Peptide - 2483P from ProSci Category Peptide Species Human

TCCR Peptide - 2481P from ProSci Category Peptide Species Human

WSX 1 Recombinant Protein - 96-455 from ProSci Category Protein Prices $375.00 Sizes 100 µg Source HEK293 cells Species Human

IL27RA fusion protein - ag2956 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

IL27RA fusion protein - ag2867 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

IL27RA fusion protein - ag9133 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human Il27RA, MIgG2a Fc-tagged - Il27RA-782H from Creative Biomart Category Protein Source CHO cell Species Human

Recombinant Human IL27RA, HIgG1 Fc-tagged - IL27RA-783H from Creative Biomart Category Protein Source CHO cell Species Human

Recombinant Human Interleukin 27 Receptor, Alpha, Fc Chimera - IL27RA-781H from Creative Biomart Category Protein Source Escherichia Coli.

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