Pea15a

Gene Symbol Pea15a
Entrez Gene 18611
Alt Symbol Mat1, PEA-15, Pea15, Pkcs15
Species Mouse
Gene Type protein-coding
Description phosphoprotein enriched in astrocytes 15A
Other Description 15 kDa phosphoprotein enriched in astrocytes|astrocytic phosphoprotein PEA-15|mammary transforming gene 1|phosphoprotein enriched in astrocytes 15
Swissprots Q3U5N7 Q62048
Accessions CAA60387 EDL39031 EDL39032 EDL39033 Q62048 AK077421 AK089070 BAC40734 AK153141 BAE31752 AK153493 BAE32041 AK161635 BAE36504 AK161977 BAE36662 AK179140 BC038282 AAH38282 BC092079 BY122161 G49234 L31958 AAC37665 XM_006496702 XP_006496765 NM_011063 NP_035193
Function Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10926929}. Note=Associated with microtubules.
Tissue Specificity Predominantly expressed in the brain. Low levels in some peripheral organs.

Mouse PEA15A Gene cDNA Clone - orb144684 from Biorbyt

Prices $255.00
Sizes 10 μg
Species Mouse

Human Pea15a ORF clone (NM_011063.2) - CDCL147931 from Creative biogene

Species Mouse
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