Gene Symbol | ERP44 |
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Entrez Gene | 23071 |
Alt Symbol | PDIA10, TXNDC4 |
Species | Human |
Gene Type | protein-coding |
Description | endoplasmic reticulum protein 44 |
Other Description | ER protein 44|endoplasmic reticulum resident protein 44|endoplasmic reticulum resident protein 44 kDa|protein disulfide isomerase family A, member 10|thioredoxin domain containing 4 (endoplasmic reticulum)|thioredoxin domain-containing protein 4 |
Swissprots | Q9BS26 Q5VWZ7 Q6UW14 Q8WX67 Q4VXC1 O60319 |
Accessions | CAF86876 EAW58922 EAW58923 Q9BS26 AB011145 BAA25499 AJ344330 CAC87611 AK075024 BAG52054 AY359048 AAQ89407 BC005374 AAH05374 BQ881761 BX648519 NM_015051 NP_055866 |
Function | Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum. {ECO:0000269|PubMed:11847130, ECO:0000269|PubMed:14517240}. |
Subcellular Location | Endoplasmic reticulum lumen. |
TXNDC4 CRISPR/Cas9 KO Plasmid (h) - sc-405173 from Santa Cruz Biotechnology
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TXNDC4 HDR Plasmid (h) - sc-405173-HDR from Santa Cruz Biotechnology
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TXNDC4 Double Nickase Plasmid (h) - sc-405173-NIC from Santa Cruz Biotechnology
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TXNDC4 Double Nickase Plasmid (h2) - sc-405173-NIC-2 from Santa Cruz Biotechnology
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TXNDC4 CRISPR Activation Plasmid (h) - sc-405173-ACT from Santa Cruz Biotechnology
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TXNDC4 CRISPR Activation Plasmid (h2) - sc-405173-ACT-2 from Santa Cruz Biotechnology
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TXNDC4 Lentiviral Activation Particles (h) - sc-405173-LAC from Santa Cruz Biotechnology
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TXNDC4 Lentiviral Activation Particles (h2) - sc-405173-LAC-2 from Santa Cruz Biotechnology
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TXNDC4 siRNA (h) - sc-92957 from Santa Cruz Biotechnology
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TXNDC4 shRNA Plasmid (h) - sc-92957-SH from Santa Cruz Biotechnology
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TXNDC4 shRNA (h) Lentiviral Particles - sc-92957-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU144031 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7977 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7977 from Sigma-Aldrich
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ERP44 siRNA (Human) - CRH7976 from Cohesion Biosciences
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ERP44 RNAi - H00023071-R01 from Novus Biologicals
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ERP44 - MBS8231056 from MyBioSource
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shRNA set against Human ERP44 (NM_015051.1) - SHH287253 from Creative biogene
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shRNA set against Human TXNDC4(NM_015051.1) - SHH223854 from Creative biogene
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ERP44 shRNA Plasmid (Human) - CHH7976 from Cohesion Biosciences
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ERP44 miRNA 3'UTR clone - MiUTR1H-10899 from Creative biogene
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