HOMER2

Gene Symbol	HOMER2
Entrez Gene	9455
Alt Symbol	ACPD, CPD, HOMER-2, VESL-2
Species	Human
Gene Type	protein-coding
Description	homer scaffolding protein 2
Other Description	cupidin|homer homolog 2|homer homolog 3|homer protein homolog 2|homer, neuronal immediate early gene, 2
Swissprots	Q9NSB6 Q9UNT7 Q9NSB7 O95269 O95349 Q9NSB8
Accessions	EAW62435 EAW62436 Q9NSB8 AF081530 AAD13748 AF093263 AAC71027 AF093264 AAC71028 AK292772 BAF85461 AY062316 AAL65744 BC012109 AAH12109 BC044934 BI666912 CB321822 CR936744 DQ892324 ABM83250 DQ895526 ABM86452 Y19025 CAB75537 Y19026 CAB75538 Y19027 CAB75539 Y19028 CAB75540 XM_005272448 XP_005272505 XM_005272449 XP_005272506 XM_006720775 XP_006720838 XM_006720776 XP_006720839 XM_011522231 XP_011520533 XM_011522232 XP_011520534 XM_011522233 XP_011520535 XM_011522234 XP_011520536 NM_004839 NP_004830 NM_199330 NP_955362 NM_199331 NM_199332
Function	Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses.
Subcellular Location	Cytoplasm. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Note=Postsynaptic density of neuronal cells. The stabilization and clustering of the metabotropic glutamate receptors appears to be mediated by isoform 1 and isoform 2 at the cell surface.
Top Pathways	Glutamatergic synapse

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HOMER2 full length protein - ab124559 from Abcam Category Protein Source E. coli Species Human

Human HOMER2 protein fragment - ab127209 from Abcam Category Protein Source E. coli Species Human

HOMER2 / Homer 2 Antibody Blocking Peptide - LS-E22567 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HOMER2 Recombinant Protein - H00009455-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human HOMER2 Protein - NBP1-99043 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E. coli Species Human

Human HOMER2 protein - orb168509 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

HOMER2 protein (His tag) - 80R-2224 from Fitzgerald Category Protein Prices $270.00 Sizes 50 µg Source E.coli

HOMER2 (1-343, His-tag) - AR50307PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

HOMER2 (1-343, His-tag) - AR50307PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

HOMER2 - H00009455-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

HOMER2 - H00009455-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

HOMER2, 1-343aa, Human, His tag, E.coli - 01-P1482 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

HOMER2 fusion protein - ag1606 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human Homer Homolog-2 Protein - BP002441-PRO-1072 from Syd Labs Category Protein Prices $160.00, $5,200.00 Sizes 10 µg, 1 mg Source E. coli-derived. Species Human

HOMER2, 1-343aa , Human, His tag, E.coli - GWB-P0556J from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Source E.coli Species Human

Recombinant Human HOMER2, GST-tagged - HOMER2-13880H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Homer protein homolog 2(HOMER2) - CSB-YP885720HU CSB-EP885720HU CSB-BP885720HU CSB-MP885720HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HOMER2, 1-343aa, Human, His tag, E.coli - ATGP1482 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 10 µg, 50 µg, 250 µg Species Human

HOMER2 (transcript variant 1) - TP304165 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

HOMER2 (transcript variant 2) - TP323154 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

HOMER2 Recombinant Protein Antigen - NBP1-85487PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

HOMER2 Peptide, Human - M34GP07173H from Creative Peptides Category Peptide Source Synthetic. Species Human

HOMER2 - PAT-81522-1 from Nordic BioSite Category Protein Species Human

HOMER2 - PAT-81522-2 from Nordic BioSite Category Protein Species Human

Homer Homolog-2, Recombinant Protein - MBS144488 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

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