Gene Symbol | RASA4 |
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Entrez Gene | 10156 |
Alt Symbol | CAPRI, GAPL |
Species | Human |
Gene Type | protein-coding |
Description | RAS p21 protein activator 4 |
Other Description | Ca2+-promoted Ras inactivator|calcium-promoted Ras inactivator|ras GTPase-activating protein 4|rasGAP-activating-like protein 2 |
Swissprots | Q96QU0 Q86UW3 Q14CQ4 O60286 O43374 |
Accessions | AAB97935 AAP22345 EAW61133 O43374 AB011110 BAA25464 AK026441 AK093486 AK302370 BAG63692 AK308653 AK310176 AK315928 BAH14299 BC110873 AAI10874 BC113663 AAI13664 BC143584 AAI43585 BC143585 BG289308 BQ890546 DA028746 DA841834 DB114101 HQ258652 ADR83403 XM_005250104 XP_005250161 XM_011515723 XP_011514025 XR_428164 XR_927325 NM_001079877 NP_001073346 NM_006989 NP_008920 |
Function | Ca(2+)-dependent Ras GTPase-activating protein, that switches off the Ras-MAPK pathway following a stimulus that elevates intracellular calcium. Functions as an adaptor for Cdc42 and Rac1 during FcR-mediated phagocytosis. {ECO:0000269|PubMed:11448776}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:11448776}. Cell membrane {ECO:0000269|PubMed:11448776}; Peripheral membrane protein {ECO:0000269|PubMed:11448776}. Note=Localized to the cytosol as a result of its lack of phosphoinositide binding activity. Upon agonist-stimulated calcium mobilization, utilizes the C2A and C2B domains to associate with the plasma membrane. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:11448776}. |
RASA4 (S-17) - sc-160709 from Santa Cruz Biotechnology
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Anti-RASA4 antibody - ab151232 from Abcam
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Anti-RASA4 antibody - ab150899 from Abcam
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Anti-RASA4 antibody - ab127760 from Abcam
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Anti-RASA4 antibody [EPR10515] - ab157190 from Abcam
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Anti-RASA4 / CAPRI Antibody - LS-C341018 from LifeSpan Bioscience
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Anti-RASA4 / CAPRI Antibody (N-Terminus) - LS-C155688 from LifeSpan Bioscience
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RASA4 Antibody - NBP2-13203 from Novus Biologicals
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RASA4 Antibody - NBP2-15089 from Novus Biologicals
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RASA4 Antibody - NBP2-15090 from Novus Biologicals
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Anti-RASA4 (N-terminal) antibody produced in rabbit - SAB2700149 from Sigma-Aldrich
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CAPRI-Antibody - AP51836 from Abgent, a WuXi AppTec company
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CAPRI Antibody - abx008358 from Abbexa
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RASA4 / CAPRI antibody - H00010156-B01P from Acris Antibodies
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RASA4 Antibody - 40069 from Signalway Antibody
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CAPRI, Polyclonal Antibody - MBS822296 from MyBioSource
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RASA4 Polyclonal Antibody - ESAP11686 from Elabscience
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RASA4 Polyclonal Antibody - ESAP15630 from Elabscience
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Anti-RASA4 (aa 585-657) polyclonal antibody - DPABH-03047 from Creative Diagnostics
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Anti-RASA4 (aa 20-803) polyclonal antibody - DPABH-03353 from Creative Diagnostics
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Anti-RASA4 (aa 20-210) polyclonal antibody - DPABH-23296 from Creative Diagnostics
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Anti-RASA4 monoclonal antibody, clone FQS21626 - DCABH-4815 from Creative Diagnostics
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RASA4 Polyclonal Antibody - PA5-31885 from Thermo Fisher Scientific
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RASA4 Polyclonal Antibody - PA5-31934 from Thermo Fisher Scientific
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RASA4, Polyclonal Antibody - MBS2522667 from MyBioSource
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