SF3A1

Gene Symbol SF3A1
Entrez Gene 10291
Alt Symbol PRP21, PRPF21, SAP114, SF3A120
Species Human
Gene Type protein-coding
Description splicing factor 3a, subunit 1, 120kDa
Other Description SAP 114|pre-mRNA processing 21|pre-mRNA splicing factor SF3a (120 kDa subunit)|spliceosome-associated protein 114|splicing factor 3 subunit 1|splicing factor 3A subunit 1|splicing factor 3a, subunit 1, 120kD
Swissprots E9PAW1 Q15459
Accessions AAC23435 EAW59878 EAW59879 Q15459 AI681052 AK098463 AK303273 BAG64353 AU100212 AV750569 BC001976 AAH01976 BC007684 AAH07684 BF965438 BI827130 BQ212479 BQ223575 BQ437843 BQ447452 CA440158 CK300534 CR456575 CAG30461 CU013174 CAK54605 CU013462 CAK54904 DB445415 DQ892687 ABM83613 DQ895931 ABM86857 X85237 CAA59494 NM_005877 NP_005868 NM_001005409
Function Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Ubiquitously expressed.
Top Pathways Spliceosome

SF3A1 - MBS1270112 from MyBioSource

Species Human
Accession BC001976

Human SF3A1 cDNA clone(NM_001005409.1) - CDFH017345 from Creative Biomart

Species Human
Accession NM_001005409.1

Human SF3A1 cDNA clone(NM_005877.4) - CDFH017346 from Creative Biomart

Species Human
Accession NM_005877.4

Human SF3A1 ORF Clone(NM_005877.4) - CDCL175185 from Creative Biomart

Species Human
Accession NM_005877.4

human SF3A1 ORF clone - CDCH079148 from Creative Biomart

Species Human
Accession NM_001005409

human SF3A1 ORF clone - CDCH079149 from Creative Biomart

Species Human
Accession NM_001005409

human SF3A1 ORF clone - CDCH079150 from Creative Biomart

Species Human
Accession NM_001005409

human SF3A1 ORF clone - CDCH079151 from Creative Biomart

Species Human
Accession NM_001005409

Human SF3A1 ORF Clone(NM_005877.4) - CDCR291511 from Creative Biomart

Species Human
Accession NM_005877.4

Human SF3A1 ORF Clone(NM_005877.4) - CDCR291512 from Creative Biomart

Species Human
Accession NM_005877.4

Human SF3A1 ORF Clone(NM_005877.4) - CDCR291513 from Creative Biomart

Species Human
Accession NM_005877.4

Human SF3A1 ORF Clone(NM_001005409.1) - CDCR339719 from Creative Biomart

Species Human
Accession NM_001005409.1

Human SF3A1 ORF Clone(NM_001005409.1) - CDCR339720 from Creative Biomart

Species Human
Accession NM_001005409.1

Human SF3A1 ORF Clone(NM_005877.4) - CDCR291511 from Creative biogene

Species Human

human SF3A1 ORF clone (NM_001005409.1) - CDCH079150 from Creative biogene

Species Human

Human SF3A1 ORF Clone (BC001976) - CDCS406247 from Creative biogene

Species Human
Accession Q15459

Human SF3A1 cDNA Clone(NM_001005409.1) - CDFH017345 from Creative biogene

Species Human

Human SF3A1 cDNA Clone(NM_005877.4) - CDFH017346 from Creative biogene

Species Human
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