SF3A1

Gene Symbol SF3A1
Entrez Gene 10291
Alt Symbol PRP21, PRPF21, SAP114, SF3A120
Species Human
Gene Type protein-coding
Description splicing factor 3a, subunit 1, 120kDa
Other Description SAP 114|pre-mRNA processing 21|pre-mRNA splicing factor SF3a (120 kDa subunit)|spliceosome-associated protein 114|splicing factor 3 subunit 1|splicing factor 3A subunit 1|splicing factor 3a, subunit 1, 120kD
Swissprots E9PAW1 Q15459
Accessions AAC23435 EAW59878 EAW59879 Q15459 AI681052 AK098463 AK303273 BAG64353 AU100212 AV750569 BC001976 AAH01976 BC007684 AAH07684 BF965438 BI827130 BQ212479 BQ223575 BQ437843 BQ447452 CA440158 CK300534 CR456575 CAG30461 CU013174 CAK54605 CU013462 CAK54904 DB445415 DQ892687 ABM83613 DQ895931 ABM86857 X85237 CAA59494 NM_005877 NP_005868 NM_001005409
Function Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Ubiquitously expressed.
Top Pathways Spliceosome

Human SF3A1 full length protein - ab160931 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160931 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human SF3A1 protein fragment - ab160932 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160932 on a 12.5% SDS-PAGE stained with Coomassie Blue.

SF3A1 / SF3A120 Antibody Blocking Peptide - LS-E14855 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SF3A1 / SF3A120 Antibody Blocking Peptide - LS-E14854 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human SF3A1 Protein - H00010291-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

Recombinant Human SF3A1 Protein - H00010291-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SF3A1 Blocking Peptide - 33R-7702 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SF3A1 Blocking Peptide - 33R-8124 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SF3A1 / SAP114 - H00010291-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

SF3A1 / SAP114 - H00010291-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SF3A1 / SAP114 - H00010291-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SF3A1 fusion protein - ag8494 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

SF3A1 fusion protein - ag8196 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human Splicing factor 3A subunit 1(SF3A1) - CSB-YP613594HU CSB-EP613594HU CSB-BP613594HU CSB-MP613594HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

SF3A1 / SAP114 (transcript variant 1) - TP301098 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
SF3A1 / SAP114

SF3A1 Recombinant Protein Antigen - NBP1-87215PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

SF3A1 Recombinant Protein Antigen - NBP1-87214PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

SF3A1-Antibody-Center-Blocking-Peptide - BP1932a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SF3A1-Antibody-N-term-Blocking-Peptide - BP1932b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SF3A1 Peptide, Human - M34GP14095H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Splicing factor 3A subunit 1 (SF3A1), Recombinant Protein - MBS1445032 from MyBioSource

Category Protein
Prices $1,610.00, $1,610.00, $1,840.00, $1,840.00, $2,770.00, $2,770.00, $3,235.00, $3,235.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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