Casp1

Gene Symbol Casp1
Entrez Gene 12362
Alt Symbol ICE, Il1bc
Species Mouse
Gene Type protein-coding
Description caspase 1
Other Description CASP-1|IL-1 beta-converting enzyme|IL-1B converting enzyme|IL-1BC|caspase-1|interleukin 1 beta-converting enzyme|interleukin-1 beta convertase|interleukin-1 beta-converting enzyme|p45
Swissprots P29452
Accessions AAA56992 EDL09320 EDL09321 EDL09322 EDL09323 P29452 AK132826 AK163069 BC008152 AAH08152 L03799 AAA39306 L28095 AAA20209 NM_009807 NP_033937
Function Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Subcellular Location Cytoplasm.
Tissue Specificity High level expression seen in spleen and lung, low level expression seen in brain, heart, liver, kidney, testis and skeletal muscle.
Top Pathways Amyotrophic lateral sclerosis (ALS), NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, Pertussis, Influenza A

caspase-1 CRISPR/Cas9 KO Plasmid (m) - sc-419461 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 HDR Plasmid (m) - sc-419461-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 Double Nickase Plasmid (m) - sc-419461-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 Double Nickase Plasmid (m2) - sc-419461-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 CRISPR Activation Plasmid (m) - sc-419461-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 CRISPR Activation Plasmid (m2) - sc-419461-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 Lentiviral Activation Particles (m) - sc-419461-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 Lentiviral Activation Particles (m2) - sc-419461-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 siRNA (m) - sc-29922 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

caspase-1 shRNA Plasmid (m) - sc-29922-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

caspase-1 shRNA (m) Lentiviral Particles - sc-29922-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN28012 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND28012 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CASP1 siRNA (Mouse) - CRM0504 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CASP1 - MBS827021 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse CASP1 (NM_009807.2) - SHH254929 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Casp1(NM_009807.2) - SHG142183 from Creative biogene

Category siRNA
Species Reactivities Mouse

caspase-1 CRISPR/Cas9 KO Plasmid (m2) - sc-419461-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

caspase-1 HDR Plasmid (m2) - sc-419461-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

Mouse Caspase 1 siRNA - orb279980 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

CASP1 shRNA Plasmid (Mouse) - CHM0504 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

CASP1 miRNA 3'UTR clone - MiUTR1M-02539 from Creative biogene

Species Reactivities Mouse
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