ZFAND5

Gene Symbol ZFAND5
Entrez Gene 7763
Alt Symbol ZA20D2, ZFAND5A, ZNF216
Species Human
Gene Type protein-coding
Description zinc finger, AN1-type domain 5
Other Description AN1-type zinc finger protein 5|zinc finger A20 domain-containing protein 2|zinc finger protein 216|zinc finger, A20 domain containing 2
Swissprots A8K484 O76080
Accessions AAC61801 EAW62533 EAW62534 EAW62535 EAW62536 EAW62537 O76080 AA837106 AF062346 AAC42601 AF062347 AAC42602 AI379933 AK025782 AK290849 BAF83538 AK307376 AW161082 BC011018 AAH11018 BC027707 AAH27707 BC073131 AAH73131 BG772839 BX489434 BX648551 BX649046 DA290666 DA392231 DA914616 EU446731 ABZ92260 X75687 NM_001102420 NP_001095890 NM_001102421 NP_001095891 NM_001278243 NP_001265172 NM_001278244 NP_001265173 NM_001278245 NP_001265174 NM_006007 NP_005998
Function Involved in protein degradation via the ubiquitin- proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4- induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. {ECO:0000269|PubMed:14754897}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Highly expressed in skeletal muscle. Expressed in fetal cochlea. Also expressed in infant brain, fetal heart, pancreatic islet, melanocyte, pineal gland, placenta, corneal stroma, and parathyroid tumor. Weakly expressed or undetectable in adult brain, heart, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. Expressed in rhabdomyosarcoma RD cells (at protein level). {ECO:0000269|PubMed:14754897, ECO:0000269|PubMed:9758550}.

ZNF216 (Q-17) - sc-249870 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ZNF216 (S-17) - sc-249871 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ZFAND5 antibody - ab86560 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ZFAND5 antibody (ab86560) at 1 µg/ml + HepG2 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-ZFAND5 antibody [2F4] - ab131636 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F4
All lanes : Anti-ZFAND5 antibody [2F4] (ab131636) at 1 µg/mlLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY ZFAND5 cDNALysates/proteins at 5 µg per lane.

Anti-ZFAND5 Antibody (aa108-157) - LS-C101496 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ZFAND5 antibody LS-C101496 Western blot of HepG2 cell lysate.

Anti-ZFAND5 Antibody (clone 2A2) - LS-C175321 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2A2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFAND5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFAND5.

Anti-ZFAND5 Antibody (clone 5B8) - LS-C175324 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5B8
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFAND5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFAND5.

Anti-ZFAND5 Antibody (clone 5A9) - LS-C175325 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5A9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFAND5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFAND5.

Anti-ZFAND5 Antibody (clone 2F4) - LS-C336978 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2F4
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZFAND5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ZFAND5.

Anti-ZFAND5 Antibody (clone 1D8) - LS-C175323 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D8
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-ZFAND5 mouse monoclonal antibody.

Anti-ZFAND5 Antibody (clone 9F2) - LS-C175326 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 9F2
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-ZFAND5 mouse monoclonal antibody.

Anti-ZFAND5 Antibody (clone 5H8) - LS-C175322 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5H8
IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-ZFAND5 mouse monoclonal antibody.

ZFAND5 Antibody - NBP1-80609 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: ZFAND5 Antibody [NBP1-80609] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

ZFAND5 Polyclonal Antibody - bs-10142R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-10142R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-10142R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-10142R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-10142R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, Cy3 Conjugated - bs-10142R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, Cy5 Conjugated - bs-10142R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, Cy5.5 Conjugated - bs-10142R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, Cy7 Conjugated - bs-10142R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, FITC Conjugated - bs-10142R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, Biotin Conjugated - bs-10142R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZFAND5 Polyclonal Antibody, HRP Conjugated - bs-10142R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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