ZFAND5

Gene Symbol ZFAND5
Entrez Gene 7763
Alt Symbol ZA20D2, ZFAND5A, ZNF216
Species Human
Gene Type protein-coding
Description zinc finger, AN1-type domain 5
Other Description AN1-type zinc finger protein 5|zinc finger A20 domain-containing protein 2|zinc finger protein 216|zinc finger, A20 domain containing 2
Swissprots A8K484 O76080
Accessions AAC61801 EAW62533 EAW62534 EAW62535 EAW62536 EAW62537 O76080 AA837106 AF062346 AAC42601 AF062347 AAC42602 AI379933 AK025782 AK290849 BAF83538 AK307376 AW161082 BC011018 AAH11018 BC027707 AAH27707 BC073131 AAH73131 BG772839 BX489434 BX648551 BX649046 DA290666 DA392231 DA914616 EU446731 ABZ92260 X75687 NM_001102420 NP_001095890 NM_001102421 NP_001095891 NM_001278243 NP_001265172 NM_001278244 NP_001265173 NM_001278245 NP_001265174 NM_006007 NP_005998
Function Involved in protein degradation via the ubiquitin- proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4- induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. {ECO:0000269|PubMed:14754897}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Highly expressed in skeletal muscle. Expressed in fetal cochlea. Also expressed in infant brain, fetal heart, pancreatic islet, melanocyte, pineal gland, placenta, corneal stroma, and parathyroid tumor. Weakly expressed or undetectable in adult brain, heart, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. Expressed in rhabdomyosarcoma RD cells (at protein level). {ECO:0000269|PubMed:14754897, ECO:0000269|PubMed:9758550}.

Human-ZFAND5-cDNA-Clone - DC03058 from Abgent, a WuXi AppTec company

Prices $287.55
Sizes 10 µg
Species Human
Accession BC011018

ZFAND5 - MBS1273566 from MyBioSource

Species Human
Accession BC011018

Human ZFAND5 cDNA clone(NM_001102421.1) - CDFH021572 from Creative Biomart

Species Human
Accession NM_001102421.1

Human ZFAND5 cDNA clone(NM_001102420.1) - CDFH021573 from Creative Biomart

Species Human
Accession NM_001102420.1

Human ZFAND5 ORF Clone(NM_001102420.1) - CDCR347410 from Creative Biomart

Species Human
Accession NM_001102420.1

Human ZFAND5 ORF Clone(NM_001102420.1) - CDCR347411 from Creative Biomart

Species Human
Accession NM_001102420.1

Human ZFAND5 ORF Clone(NM_001102421.1) - CDCR347412 from Creative Biomart

Species Human
Accession NM_001102421.1

Human ZFAND5 ORF Clone(NM_001102421.1) - CDCR347413 from Creative Biomart

Species Human
Accession NM_001102421.1

human ZFAND5 ORF clone - CDCH102990 from Creative Biomart

Species Human
Accession NM_001102420

human ZFAND5 ORF clone - CDCH102991 from Creative Biomart

Species Human
Accession NM_001102420

Human ZFAND5 ORF Clone(NM_006007.2) - CDCL181750 from Creative Biomart

Species Human
Accession NM_006007.2

Human ZFAND5 ORF Clone(NM_001102420.1) - CDCR347410 from Creative biogene

Species Human

Human ZFAND5 ORF Clone(NM_001102421.1) - CDCR347412 from Creative biogene

Species Human

Human ZFAND5 ORF Clone (BC011018) - CDCS407557 from Creative biogene

Species Human
Accession O76080

Human ZFAND5 cDNA Clone(NM_001102421.1) - CDFH021572 from Creative biogene

Species Human

Human ZFAND5 cDNA Clone(NM_001102420.1) - CDFH021573 from Creative biogene

Species Human
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