ZFAND5

Gene Symbol ZFAND5
Entrez Gene 7763
Alt Symbol ZA20D2, ZFAND5A, ZNF216
Species Human
Gene Type protein-coding
Description zinc finger, AN1-type domain 5
Other Description AN1-type zinc finger protein 5|zinc finger A20 domain-containing protein 2|zinc finger protein 216|zinc finger, A20 domain containing 2
Swissprots A8K484 O76080
Accessions AAC61801 EAW62533 EAW62534 EAW62535 EAW62536 EAW62537 O76080 AA837106 AF062346 AAC42601 AF062347 AAC42602 AI379933 AK025782 AK290849 BAF83538 AK307376 AW161082 BC011018 AAH11018 BC027707 AAH27707 BC073131 AAH73131 BG772839 BX489434 BX648551 BX649046 DA290666 DA392231 DA914616 EU446731 ABZ92260 X75687 NM_001102420 NP_001095890 NM_001102421 NP_001095891 NM_001278243 NP_001265172 NM_001278244 NP_001265173 NM_001278245 NP_001265174 NM_006007 NP_005998
Function Involved in protein degradation via the ubiquitin- proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4- induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. {ECO:0000269|PubMed:14754897}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Highly expressed in skeletal muscle. Expressed in fetal cochlea. Also expressed in infant brain, fetal heart, pancreatic islet, melanocyte, pineal gland, placenta, corneal stroma, and parathyroid tumor. Weakly expressed or undetectable in adult brain, heart, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. Expressed in rhabdomyosarcoma RD cells (at protein level). {ECO:0000269|PubMed:14754897, ECO:0000269|PubMed:9758550}.

ZNF216 CRISPR/Cas9 KO Plasmid (h) - sc-417001 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF216 HDR Plasmid (h) - sc-417001-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF216 Double Nickase Plasmid (h) - sc-417001-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF216 Double Nickase Plasmid (h2) - sc-417001-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF216 CRISPR Activation Plasmid (h) - sc-417001-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF216 CRISPR Activation Plasmid (h2) - sc-417001-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF216 Lentiviral Activation Particles (h) - sc-417001-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF216 Lentiviral Activation Particles (h2) - sc-417001-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNF216 siRNA (h) - sc-92627 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF216 shRNA Plasmid (h) - sc-92627-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNF216 shRNA (h) Lentiviral Particles - sc-92627-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZFAND5 RNAi - H00007763-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU159731 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23164 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23164 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09587 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09587

ZFAND5 siRNA (Human) - CRH5255 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZFAND5 - MBS8230127 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZFAND5 (NM_006007.2) - SHH450196 from Creative biogene

Category siRNA
Species Reactivities Human

ZFAND5 shRNA Plasmid (Human) - CHH5255 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ZFAND5 miRNA 3'UTR clone - MiUTR1H-11425 from Creative biogene

Species Reactivities Human
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