ZFAND5

Gene Symbol	ZFAND5
Entrez Gene	7763
Alt Symbol	ZA20D2, ZFAND5A, ZNF216
Species	Human
Gene Type	protein-coding
Description	zinc finger, AN1-type domain 5
Other Description	AN1-type zinc finger protein 5|zinc finger A20 domain-containing protein 2|zinc finger protein 216|zinc finger, A20 domain containing 2
Swissprots	A8K484 O76080
Accessions	AAC61801 EAW62533 EAW62534 EAW62535 EAW62536 EAW62537 O76080 AA837106 AF062346 AAC42601 AF062347 AAC42602 AI379933 AK025782 AK290849 BAF83538 AK307376 AW161082 BC011018 AAH11018 BC027707 AAH27707 BC073131 AAH73131 BG772839 BX489434 BX648551 BX649046 DA290666 DA392231 DA914616 EU446731 ABZ92260 X75687 NM_001102420 NP_001095890 NM_001102421 NP_001095891 NM_001278243 NP_001265172 NM_001278244 NP_001265173 NM_001278245 NP_001265174 NM_006007 NP_005998
Function	Involved in protein degradation via the ubiquitin- proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4- induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation. {ECO:0000269|PubMed:14754897}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Tissue Specificity	Highly expressed in skeletal muscle. Expressed in fetal cochlea. Also expressed in infant brain, fetal heart, pancreatic islet, melanocyte, pineal gland, placenta, corneal stroma, and parathyroid tumor. Weakly expressed or undetectable in adult brain, heart, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. Expressed in rhabdomyosarcoma RD cells (at protein level). {ECO:0000269|PubMed:14754897, ECO:0000269|PubMed:9758550}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ZFAND5 full length protein - ab202212 from Abcam Category Protein Source E. coli Species Human

Human ZFAND5 full length protein - ab127273 from Abcam Category Protein Source E. coli Species Human

ZFAND5 Antibody Blocking Peptide - LS-E12194 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ZFAND5 Recombinant Protein - H00007763-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ZFAND5 Partial Recombinant Protein - H00007763-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

ZFAND5 protein (His tag) - 80R-4066 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

ZA20D2 (1-213, His-tag) - AR51751PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

ZA20D2 (1-213, His-tag) - AR51751PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

ZA20D2 - H00007763-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ZA20D2 - H00007763-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ZA20D2 - H00007763-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ZA20D2 - H00007763-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ZFAND5 fusion protein - ag19441 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ZFAND5 fusion protein - Ag19311 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human ZFAND5, His-tagged - ZFAND5-3447H from Creative Biomart Category Protein Source E. Coli or Yeast Species Human

Recombinant Human AN1-type zinc finger protein 5(ZFAND5) - CSB-YP026431HU CSB-EP026431HU CSB-BP026431HU CSB-MP026431HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

ZA20D2 (transcript variant c) - TP309943 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ZA20D2 (transcript variant a) - TP321072 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ZA20D2 (transcript variant b) - TP321129 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ZA20D2 (full length, C-term DDK tag, transcript variant c) - TP710147 from Acris Antibodies Category Protein Prices $399.00 Sizes 20 µg Source SF9 cells Species Human

ZFAND5, Recombinant Protein - MBS206074 from MyBioSource Category Protein Prices $310.00, $720.00 Sizes 100 µg, 500 µg Source E Coli Species Human

AN1-type zinc finger protein 5 (ZFAND5) , Recombinant Protein - MBS1214828 from MyBioSource Category Protein Prices $1,445.00, $1,445.00, $1,910.00, $1,910.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

ZFAND5 Recombinant Protein Antigen - NBP1-80609PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ZFAN5-Antibody-C-term-Blocking-peptide - BP5929b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ZFAND5 Peptide, Human - M34GP17778H from Creative Peptides Category Peptide Source Synthetic. Species Human

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